STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGFBPL1Insulin-like growth factor-binding protein-like 1; IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). (274 aa)    
Predicted Functional Partners:
FBXO47
F-box protein 47.
   
    0.742
LIX1
Limb and CNS expressed 1.
   
    0.707
MIPOL1
Mirror-image polydactyly 1.
      
 0.692
C3H1orf109
Chromosome 3 C1orf109 homolog.
   
    0.587
LYSMD2
LysM and putative peptidoglycan-binding domain-containing protein 2.
   
    0.558
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa.
      
 0.550
TAF1C
TATA-box binding protein associated factor, RNA polymerase I subunit C.
      
 0.520
RFK
Riboflavin kinase.
      
 0.512
CALHM4
Calcium homeostasis modulator family member 4.
   
    0.502
SOGA1
Suppressor of glucose, autophagy associated 1.
      
 0.500
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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