STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS54Serine protease 54. (327 aa)    
Predicted Functional Partners:
TEX55
Uncharacterized protein.
      
 0.865
PRSS37
Probable inactive serine protease 37; Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system; Belongs to the peptidase S1 family.
      
 0.807
OR5C1
Olfactory receptor.
    
 
 0.785
TEX37
Testis-expressed sequence 37 protein.
    
 
 0.742
OR4X1
Olfactory receptor.
    
 
 0.692
GPR25
G protein-coupled receptor 25; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.689
DDI1
Protein DDI1 homolog 1; Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity).
      
 0.684
TAC4
Uncharacterized protein.
      
 0.684
ADAM21
ADAM metallopeptidase domain 21.
      
 0.662
ADAM21-2
Uncharacterized protein.
      
 0.662
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.