node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | LRRTM2 | ENSBTAP00000073270 | ENSBTAP00000018866 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine rich repeat transmembrane neuronal 2. | 0.747 |
ADGRL1 | NRXN1 | ENSBTAP00000073270 | ENSBTAP00000053469 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N- terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect [...] | 0.576 |
ADGRL3 | LRRTM2 | ENSBTAP00000049222 | ENSBTAP00000018866 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine rich repeat transmembrane neuronal 2. | 0.793 |
ADGRL3 | NLGN1 | ENSBTAP00000049222 | ENSBTAP00000042636 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Neuroligin 1. | 0.575 |
ADGRL3 | NRXN1 | ENSBTAP00000049222 | ENSBTAP00000053469 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N- terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect [...] | 0.653 |
ADGRL3 | NRXN2 | ENSBTAP00000049222 | ENSBTAP00000000307 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Neurexin 2. | 0.572 |
ADGRL3 | NRXN3-2 | ENSBTAP00000049222 | ENSBTAP00000052163 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Neurexin-3-beta, C-terminal fragment; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis (By similarity); Belongs to the neurexin family. | 0.560 |
FAM163B | LRRTM2 | ENSBTAP00000061636 | ENSBTAP00000018866 | Uncharacterized protein. | Leucine rich repeat transmembrane neuronal 2. | 0.722 |
FAM163B | ZC2HC1B | ENSBTAP00000061636 | ENSBTAP00000010726 | Uncharacterized protein. | Zinc finger C2HC domain-containing protein 1B; Belongs to the ZC2HC1 family. | 0.909 |
LRRTM2 | ADGRL1 | ENSBTAP00000018866 | ENSBTAP00000073270 | Leucine rich repeat transmembrane neuronal 2. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | 0.747 |
LRRTM2 | ADGRL3 | ENSBTAP00000018866 | ENSBTAP00000049222 | Leucine rich repeat transmembrane neuronal 2. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.793 |
LRRTM2 | FAM163B | ENSBTAP00000018866 | ENSBTAP00000061636 | Leucine rich repeat transmembrane neuronal 2. | Uncharacterized protein. | 0.722 |
LRRTM2 | NLGN1 | ENSBTAP00000018866 | ENSBTAP00000042636 | Leucine rich repeat transmembrane neuronal 2. | Neuroligin 1. | 0.766 |
LRRTM2 | NRXN1 | ENSBTAP00000018866 | ENSBTAP00000053469 | Leucine rich repeat transmembrane neuronal 2. | Neurexin-1; Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N- terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect [...] | 0.925 |
LRRTM2 | NRXN1-2 | ENSBTAP00000018866 | ENSBTAP00000044872 | Leucine rich repeat transmembrane neuronal 2. | Neurexin-1-beta; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity). | 0.972 |
LRRTM2 | NRXN2 | ENSBTAP00000018866 | ENSBTAP00000000307 | Leucine rich repeat transmembrane neuronal 2. | Neurexin 2. | 0.910 |
LRRTM2 | NRXN3-2 | ENSBTAP00000018866 | ENSBTAP00000052163 | Leucine rich repeat transmembrane neuronal 2. | Neurexin-3-beta, C-terminal fragment; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis (By similarity); Belongs to the neurexin family. | 0.879 |
LRRTM2 | TMPRSS9 | ENSBTAP00000018866 | ENSBTAP00000000958 | Leucine rich repeat transmembrane neuronal 2. | Transmembrane serine protease 9; Belongs to the peptidase S1 family. | 0.721 |
LRRTM2 | ZC2HC1B | ENSBTAP00000018866 | ENSBTAP00000010726 | Leucine rich repeat transmembrane neuronal 2. | Zinc finger C2HC domain-containing protein 1B; Belongs to the ZC2HC1 family. | 0.722 |
NLGN1 | ADGRL3 | ENSBTAP00000042636 | ENSBTAP00000049222 | Neuroligin 1. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.575 |