node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCSH | IBA57 | ENSBTAP00000008936 | ENSBTAP00000019861 | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family. | Iron-sulfur cluster assembly factor IBA57. | 0.542 |
GCSH | LIAS | ENSBTAP00000008936 | ENSBTAP00000019299 | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.933 |
GCSH | LIPT1 | ENSBTAP00000008936 | ENSBTAP00000005171 | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family. | Lipoyltransferase 1, mitochondrial; Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes; Belongs to the LplA family. | 0.906 |
GCSH | LIPT2 | ENSBTAP00000008936 | ENSBTAP00000010820 | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.935 |
IBA57 | GCSH | ENSBTAP00000019861 | ENSBTAP00000008936 | Iron-sulfur cluster assembly factor IBA57. | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family. | 0.542 |
IBA57 | ISCA1 | ENSBTAP00000019861 | ENSBTAP00000060430 | Iron-sulfur cluster assembly factor IBA57. | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | 0.985 |
IBA57 | ISCA2 | ENSBTAP00000019861 | ENSBTAP00000029272 | Iron-sulfur cluster assembly factor IBA57. | Iron-sulfur cluster assembly 2 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family. | 0.991 |
IBA57 | LIAS | ENSBTAP00000019861 | ENSBTAP00000019299 | Iron-sulfur cluster assembly factor IBA57. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.850 |
IBA57 | LIPT1 | ENSBTAP00000019861 | ENSBTAP00000005171 | Iron-sulfur cluster assembly factor IBA57. | Lipoyltransferase 1, mitochondrial; Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes; Belongs to the LplA family. | 0.504 |
IBA57 | LIPT2 | ENSBTAP00000019861 | ENSBTAP00000010820 | Iron-sulfur cluster assembly factor IBA57. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.546 |
IBA57 | LYRM4 | ENSBTAP00000019861 | ENSBTAP00000042040 | Iron-sulfur cluster assembly factor IBA57. | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; Belongs to the complex I LYR family. | 0.873 |
IBA57 | NFS1 | ENSBTAP00000019861 | ENSBTAP00000009149 | Iron-sulfur cluster assembly factor IBA57. | NFS1 protein. | 0.850 |
IBA57 | NFU1 | ENSBTAP00000019861 | ENSBTAP00000072777 | Iron-sulfur cluster assembly factor IBA57. | NFU1 iron-sulfur cluster scaffold. | 0.897 |
ISCA1 | IBA57 | ENSBTAP00000060430 | ENSBTAP00000019861 | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | Iron-sulfur cluster assembly factor IBA57. | 0.985 |
ISCA1 | ISCA2 | ENSBTAP00000060430 | ENSBTAP00000029272 | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | Iron-sulfur cluster assembly 2 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family. | 0.999 |
ISCA1 | LIAS | ENSBTAP00000060430 | ENSBTAP00000019299 | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.835 |
ISCA1 | LYRM4 | ENSBTAP00000060430 | ENSBTAP00000042040 | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | LYR motif-containing protein 4; Required for nuclear and mitochondrial iron-sulfur protein biosynthesis; Belongs to the complex I LYR family. | 0.815 |
ISCA1 | NFS1 | ENSBTAP00000060430 | ENSBTAP00000009149 | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | NFS1 protein. | 0.917 |
ISCA1 | NFU1 | ENSBTAP00000060430 | ENSBTAP00000072777 | Iron-sulfur cluster assembly 1 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly. | NFU1 iron-sulfur cluster scaffold. | 0.941 |
ISCA2 | IBA57 | ENSBTAP00000029272 | ENSBTAP00000019861 | Iron-sulfur cluster assembly 2 homolog, mitochondrial; Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. Belongs to the HesB/IscA family. | Iron-sulfur cluster assembly factor IBA57. | 0.991 |