STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLEC1AC-type lectin domain family 1 member A. (278 aa)    
Predicted Functional Partners:
PDPN
Podoplanin.
    
 
 0.755
CLEC4D
C-type lectin domain family 4 member D.
   
  
 0.656
CLEC14A
C-type lectin domain family 14, member A.
   
 
 0.587
CLEC4E
C-type lectin domain family 4 member E.
    
 
 0.528
PPM1J
Protein phosphatase, Mg2+/Mn2+ dependent 1J.
      
 0.472
TYROBP
TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]
   
 
 0.469
CLEC4G
C-type lectin domain family 4 member G.
   
  
 0.467
RNF217
RBR-type E3 ubiquitin transferase.
      
 0.460
TREM2
Triggering receptor expressed on myeloid cells 2.
   
  
 0.456
AXL
AXL receptor tyrosine kinase.
    
 
 0.412
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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