Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATXN7L3B | TNFAIP8 | ENSBTAP00000046438 | ENSBTAP00000019342 | Ataxin 7 like 3B. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.551 |
| CCNDBP1 | CSNK2A2 | ENSBTAP00000017326 | ENSBTAP00000018322 | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | 0.448 |
| CCNDBP1 | ENSBTAP00000073398 | ENSBTAP00000017326 | ENSBTAP00000073398 | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.422 |
| CCNDBP1 | GDI2 | ENSBTAP00000017326 | ENSBTAP00000073322 | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | 0.422 |
| CCNDBP1 | TNFAIP8 | ENSBTAP00000017326 | ENSBTAP00000019342 | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.510 |
| CLECL1 | TNFAIP8 | ENSBTAP00000051719 | ENSBTAP00000019342 | LOC618591 protein. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.524 |
| CSNK2A2 | CCNDBP1 | ENSBTAP00000018322 | ENSBTAP00000017326 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | 0.448 |
| CSNK2A2 | TNFAIP8 | ENSBTAP00000018322 | ENSBTAP00000019342 | Casein kinase II subunit alpha; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoin [...] | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.438 |
| ENSBTAP00000073398 | CCNDBP1 | ENSBTAP00000073398 | ENSBTAP00000017326 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | 0.422 |
| ENSBTAP00000073398 | GDI2 | ENSBTAP00000073398 | ENSBTAP00000073322 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | 0.406 |
| ENSBTAP00000073398 | TNFAIP8 | ENSBTAP00000073398 | ENSBTAP00000019342 | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.412 |
| GDI2 | CCNDBP1 | ENSBTAP00000073322 | ENSBTAP00000017326 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription (By similarity); Belongs to the CCNDBP1 family. | 0.422 |
| GDI2 | ENSBTAP00000073398 | ENSBTAP00000073322 | ENSBTAP00000073398 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. | 0.406 |
| GDI2 | TNFAIP8 | ENSBTAP00000073322 | ENSBTAP00000019342 | Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.412 |
| GTPBP2 | PHYHIP | ENSBTAP00000007903 | ENSBTAP00000020921 | GTP binding protein 2. | Phytanoyl-CoA hydroxylase-interacting protein; Its interaction with PHYH suggests a role in the development of the central system; Belongs to the PHYHIP family. | 0.572 |
| GTPBP2 | TNFAIP8 | ENSBTAP00000007903 | ENSBTAP00000019342 | GTP binding protein 2. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.429 |
| PHYHIP | GTPBP2 | ENSBTAP00000020921 | ENSBTAP00000007903 | Phytanoyl-CoA hydroxylase-interacting protein; Its interaction with PHYH suggests a role in the development of the central system; Belongs to the PHYHIP family. | GTP binding protein 2. | 0.572 |
| PHYHIP | TNFAIP8 | ENSBTAP00000020921 | ENSBTAP00000019342 | Phytanoyl-CoA hydroxylase-interacting protein; Its interaction with PHYH suggests a role in the development of the central system; Belongs to the PHYHIP family. | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.453 |
| RASA3 | RIC8A | ENSBTAP00000026598 | ENSBTAP00000002646 | Ras GTPase-activating protein 3; Inhibitory regulator of the Ras-cyclic AMP pathway. May bind inositol tetrakisphosphate (IP4). | Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)- alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation (By similarity). | 0.578 |
| RASA3 | TNFAIP8 | ENSBTAP00000026598 | ENSBTAP00000019342 | Ras GTPase-activating protein 3; Inhibitory regulator of the Ras-cyclic AMP pathway. May bind inositol tetrakisphosphate (IP4). | Tumor necrosis factor alpha-induced protein 8; Acts as a negative mediator of apoptosis. Suppresses the TNF- mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity); Belongs to the TNFAIP8 family. | 0.590 |
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