node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSBTAP00000069264 | ISOC1 | ENSBTAP00000069264 | ENSBTAP00000035516 | Nicotinamide-nucleotide adenylyltransferase. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.599 |
ENSBTAP00000069264 | ISOC2 | ENSBTAP00000069264 | ENSBTAP00000064229 | Nicotinamide-nucleotide adenylyltransferase. | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | 0.599 |
ENSBTAP00000069264 | NADSYN1 | ENSBTAP00000069264 | ENSBTAP00000074390 | Nicotinamide-nucleotide adenylyltransferase. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.832 |
ENSBTAP00000069264 | NAMPT | ENSBTAP00000069264 | ENSBTAP00000064059 | Nicotinamide-nucleotide adenylyltransferase. | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. | 0.599 |
ENSBTAP00000069264 | NAPRT | ENSBTAP00000069264 | ENSBTAP00000065613 | Nicotinamide-nucleotide adenylyltransferase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.766 |
ENSBTAP00000069264 | NMRK1 | ENSBTAP00000069264 | ENSBTAP00000063690 | Nicotinamide-nucleotide adenylyltransferase. | Nicotinamide riboside kinase 1. | 0.497 |
ENSBTAP00000069264 | QPRT | ENSBTAP00000069264 | ENSBTAP00000062942 | Nicotinamide-nucleotide adenylyltransferase. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.824 |
ISOC1 | ENSBTAP00000069264 | ENSBTAP00000035516 | ENSBTAP00000069264 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.599 |
ISOC1 | NADSYN1 | ENSBTAP00000035516 | ENSBTAP00000074390 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.466 |
ISOC1 | NAPRT | ENSBTAP00000035516 | ENSBTAP00000065613 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.747 |
ISOC1 | NMNAT1 | ENSBTAP00000035516 | ENSBTAP00000059876 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less [...] | 0.599 |
ISOC1 | NMNAT2 | ENSBTAP00000035516 | ENSBTAP00000060736 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity). Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substra [...] | 0.599 |
ISOC1 | QPRT | ENSBTAP00000035516 | ENSBTAP00000062942 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.460 |
ISOC2 | ENSBTAP00000069264 | ENSBTAP00000064229 | ENSBTAP00000069264 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinamide-nucleotide adenylyltransferase. | 0.599 |
ISOC2 | NADSYN1 | ENSBTAP00000064229 | ENSBTAP00000074390 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.482 |
ISOC2 | NAPRT | ENSBTAP00000064229 | ENSBTAP00000065613 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis; Belongs to the NAPRTase family. | 0.760 |
ISOC2 | NMNAT1 | ENSBTAP00000064229 | ENSBTAP00000059876 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less [...] | 0.599 |
ISOC2 | NMNAT2 | ENSBTAP00000064229 | ENSBTAP00000060736 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor (By similarity). Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NaAD as substra [...] | 0.599 |
ISOC2 | QPRT | ENSBTAP00000064229 | ENSBTAP00000062942 | Isochorismatase domain-containing protein 2; Belongs to the isochorismatase family. | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. | 0.495 |
NADSYN1 | ENSBTAP00000069264 | ENSBTAP00000074390 | ENSBTAP00000069264 | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Nicotinamide-nucleotide adenylyltransferase. | 0.832 |