node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AURKAIP1 | GADD45GIP1 | ENSBTAP00000061171 | ENSBTAP00000020114 | Aurora kinase A interacting protein 1. | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 0.950 |
AURKAIP1 | MRPL11 | ENSBTAP00000061171 | ENSBTAP00000063389 | Aurora kinase A interacting protein 1. | 39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family. | 0.770 |
AURKAIP1 | MRPL28 | ENSBTAP00000061171 | ENSBTAP00000022057 | Aurora kinase A interacting protein 1. | 39S ribosomal protein L28, mitochondrial; Belongs to the bacterial ribosomal protein bL28 family. | 0.930 |
AURKAIP1 | MRPL30 | ENSBTAP00000061171 | ENSBTAP00000005183 | Aurora kinase A interacting protein 1. | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. | 0.914 |
AURKAIP1 | MRPL4 | ENSBTAP00000061171 | ENSBTAP00000057411 | Aurora kinase A interacting protein 1. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.882 |
AURKAIP1 | MRPL40 | ENSBTAP00000061171 | ENSBTAP00000026501 | Aurora kinase A interacting protein 1. | Mitochondrial ribosomal protein L40. | 0.964 |
AURKAIP1 | MRPL49 | ENSBTAP00000061171 | ENSBTAP00000006689 | Aurora kinase A interacting protein 1. | 39S ribosomal protein L49, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family. | 0.868 |
AURKAIP1 | MRPL51 | ENSBTAP00000061171 | ENSBTAP00000019602 | Aurora kinase A interacting protein 1. | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | 0.858 |
AURKAIP1 | MRPL58 | ENSBTAP00000061171 | ENSBTAP00000004276 | Aurora kinase A interacting protein 1. | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. | 0.963 |
AURKAIP1 | MRPS34 | ENSBTAP00000061171 | ENSBTAP00000037370 | Aurora kinase A interacting protein 1. | 28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation. | 0.991 |
GADD45GIP1 | AURKAIP1 | ENSBTAP00000020114 | ENSBTAP00000061171 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | Aurora kinase A interacting protein 1. | 0.950 |
GADD45GIP1 | MRPL11 | ENSBTAP00000020114 | ENSBTAP00000063389 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family. | 0.970 |
GADD45GIP1 | MRPL28 | ENSBTAP00000020114 | ENSBTAP00000022057 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L28, mitochondrial; Belongs to the bacterial ribosomal protein bL28 family. | 0.963 |
GADD45GIP1 | MRPL30 | ENSBTAP00000020114 | ENSBTAP00000005183 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L30, mitochondrial; Belongs to the universal ribosomal protein uL30 family. | 0.950 |
GADD45GIP1 | MRPL4 | ENSBTAP00000020114 | ENSBTAP00000057411 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.952 |
GADD45GIP1 | MRPL40 | ENSBTAP00000020114 | ENSBTAP00000026501 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | Mitochondrial ribosomal protein L40. | 0.979 |
GADD45GIP1 | MRPL49 | ENSBTAP00000020114 | ENSBTAP00000006689 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L49, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family. | 0.980 |
GADD45GIP1 | MRPL51 | ENSBTAP00000020114 | ENSBTAP00000019602 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL51 family. | 0.979 |
GADD45GIP1 | MRPL58 | ENSBTAP00000020114 | ENSBTAP00000004276 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. | 0.995 |
GADD45GIP1 | MRPS34 | ENSBTAP00000020114 | ENSBTAP00000037370 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 28S ribosomal protein S34, mitochondrial; Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation. | 0.960 |