STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN2Nectin cell adhesion molecule 2. (539 aa)    
Predicted Functional Partners:
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
    
0.998
AFDN
Afadin, adherens junction formation factor.
   
 0.991
CD226
CD226 molecule.
    
 0.980
NECTIN3
Nectin cell adhesion molecule 3.
    
0.978
NECTIN1
Nectin cell adhesion molecule 1.
    
0.944
NECTIN4
Nectin-4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1.
    
0.911
CRTAM
Cytotoxic and regulatory T cell molecule.
     
 0.905
PARD3
Par-3 family cell polarity regulator.
    
  0.901
KLRK1
C-type lectin domain-containing protein.
      
 0.838
ENSBTAP00000073285
IG domain-containing protein.
      
 0.812
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.