node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCD1 | ZFPL1 | ENSBTAP00000027382 | ENSBTAP00000020585 | ATP-binding cassette, sub-family D (ALD), member 1. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.582 |
COPG1 | SEC13 | ENSBTAP00000017588 | ENSBTAP00000023702 | Coatomer subunit gamma-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also i [...] | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum; Belongs to the WD repeat SEC13 family. | 0.721 |
COPG1 | ZFPL1 | ENSBTAP00000017588 | ENSBTAP00000020585 | Coatomer subunit gamma-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also i [...] | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.586 |
ERC1 | RAD9A | ENSBTAP00000071004 | ENSBTAP00000016108 | ELKS/RAB6-interacting/CAST family member 1. | Cell cycle checkpoint control protein; Belongs to the rad9 family. | 0.648 |
ERC1 | ZFPL1 | ENSBTAP00000071004 | ENSBTAP00000020585 | ELKS/RAB6-interacting/CAST family member 1. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.686 |
IFT20 | ZFPL1 | ENSBTAP00000010668 | ENSBTAP00000020585 | Intraflagellar transport protein 20 homolog; Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. Plays an important role in spermatogenesis, particularly sperm [...] | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.572 |
MGAT1 | ZFPL1 | ENSBTAP00000053874 | ENSBTAP00000020585 | Mannosyl (Alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.577 |
PITPNM1 | ZFPL1 | ENSBTAP00000013851 | ENSBTAP00000020585 | Phosphatidylinositol transfer protein membrane associated 1. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.571 |
RAB32 | ZFPL1 | ENSBTAP00000012905 | ENSBTAP00000020585 | RAB32, member RAS oncogene family. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.571 |
RAD9A | ERC1 | ENSBTAP00000016108 | ENSBTAP00000071004 | Cell cycle checkpoint control protein; Belongs to the rad9 family. | ELKS/RAB6-interacting/CAST family member 1. | 0.648 |
RAD9A | ZFPL1 | ENSBTAP00000016108 | ENSBTAP00000020585 | Cell cycle checkpoint control protein; Belongs to the rad9 family. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.776 |
RCE1 | ZFPL1 | ENSBTAP00000042314 | ENSBTAP00000020585 | CAAX prenyl protease 2; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K- Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (By similarity). Belongs to the peptidase U48 family. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.624 |
SEC13 | COPG1 | ENSBTAP00000023702 | ENSBTAP00000017588 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum; Belongs to the WD repeat SEC13 family. | Coatomer subunit gamma-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also i [...] | 0.721 |
SEC13 | ZFPL1 | ENSBTAP00000023702 | ENSBTAP00000020585 | Protein SEC13 homolog; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum; Belongs to the WD repeat SEC13 family. | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | 0.724 |
ZFPL1 | ABCD1 | ENSBTAP00000020585 | ENSBTAP00000027382 | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | ATP-binding cassette, sub-family D (ALD), member 1. | 0.582 |
ZFPL1 | COPG1 | ENSBTAP00000020585 | ENSBTAP00000017588 | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | Coatomer subunit gamma-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also i [...] | 0.586 |
ZFPL1 | ERC1 | ENSBTAP00000020585 | ENSBTAP00000071004 | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | ELKS/RAB6-interacting/CAST family member 1. | 0.686 |
ZFPL1 | IFT20 | ENSBTAP00000020585 | ENSBTAP00000010668 | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | Intraflagellar transport protein 20 homolog; Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. Plays an important role in spermatogenesis, particularly sperm [...] | 0.572 |
ZFPL1 | MGAT1 | ENSBTAP00000020585 | ENSBTAP00000053874 | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | Mannosyl (Alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. | 0.577 |
ZFPL1 | PITPNM1 | ENSBTAP00000020585 | ENSBTAP00000013851 | Zinc finger protein-like 1; Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis- Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity). | Phosphatidylinositol transfer protein membrane associated 1. | 0.571 |