Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC47 | NCLN | ENSBTAP00000060375 | ENSBTAP00000069082 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 0.936 |
| CCDC47 | RAB5IF | ENSBTAP00000060375 | ENSBTAP00000029063 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | RAB5-interacting protein. | 0.845 |
| CCDC47 | RPL11 | ENSBTAP00000060375 | ENSBTAP00000027850 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.856 |
| CCDC47 | SEC61A1 | ENSBTAP00000060375 | ENSBTAP00000006494 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Protein transport protein Sec61 subunit alpha isoform 1; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post- translational transport of small presecretory proteins. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC [...] | 0.848 |
| CCDC47 | SEC61B | ENSBTAP00000060375 | ENSBTAP00000067476 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | SEC61 translocon beta subunit. | 0.845 |
| CCDC47 | TMCO1 | ENSBTAP00000060375 | ENSBTAP00000013200 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store. | 0.969 |
| CCDC47 | TMEM147 | ENSBTAP00000060375 | ENSBTAP00000021170 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.859 |
| CCDC47 | WDR83OS | ENSBTAP00000060375 | ENSBTAP00000059696 | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | Protein Asterix. | 0.952 |
| GALM | TMEM147 | ENSBTAP00000028111 | ENSBTAP00000021170 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.831 |
| GALM | TMEM63A | ENSBTAP00000028111 | ENSBTAP00000003701 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | Transmembrane protein 63A. | 0.837 |
| NCLN | CCDC47 | ENSBTAP00000069082 | ENSBTAP00000060375 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 0.936 |
| NCLN | RAB5IF | ENSBTAP00000069082 | ENSBTAP00000029063 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | RAB5-interacting protein. | 0.862 |
| NCLN | RPL11 | ENSBTAP00000069082 | ENSBTAP00000027850 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.852 |
| NCLN | SEC61A1 | ENSBTAP00000069082 | ENSBTAP00000006494 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Protein transport protein Sec61 subunit alpha isoform 1; Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post- translational transport of small presecretory proteins. Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC [...] | 0.874 |
| NCLN | SEC61B | ENSBTAP00000069082 | ENSBTAP00000067476 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | SEC61 translocon beta subunit. | 0.845 |
| NCLN | TMCO1 | ENSBTAP00000069082 | ENSBTAP00000013200 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis. In response to endoplasmic reticulum overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store. | 0.912 |
| NCLN | TMEM147 | ENSBTAP00000069082 | ENSBTAP00000021170 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.931 |
| NCLN | WDR83OS | ENSBTAP00000069082 | ENSBTAP00000059696 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Protein Asterix. | 0.850 |
| RAB5IF | CCDC47 | ENSBTAP00000029063 | ENSBTAP00000060375 | RAB5-interacting protein. | Coiled-coil domain-containing protein 47; Involved in the regulation of calcium ion homeostasis in the endoplasmic reticulum (By similarity). Required for proper protein degradation via the ERAD pathway. Has an essential role in the maintenance of endoplasmic reticulum organization during embryogenesis (By similarity). | 0.845 |
| RAB5IF | NCLN | ENSBTAP00000029063 | ENSBTAP00000069082 | RAB5-interacting protein. | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 0.862 |
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