STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASCL1Achaete-scute family bHLH transcription factor 1. (219 aa)    
Predicted Functional Partners:
MYT1L
Myelin transcription factor 1-like.
   
  
 0.902
OLIG2
Oligodendrocyte transcription factor 2.
   
 
 0.854
DLX2
Distal-less homeobox 2.
      
 0.850
NEUROG2
Neurogenin 2.
   
 
 0.821
GSX2
GS homeobox 2.
   
 
 0.779
PAX6
Paired box protein Pax-6; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity); Belongs to the paired homeobox family.
      
 0.770
DLX1
Distal-less homeobox 1.
   
  
 0.764
NEUROG1
Neurogenin 1.
   
 
 0.751
SOX10
SRY-box transcription factor 10.
    
 
 0.747
TCF12
Transcription factor 12.
   
 
 0.742
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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