STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEAD2TEA domain transcription factor 2. (451 aa)    
Predicted Functional Partners:
YAP1
Yes associated protein 1.
   
 0.993
WWTR1
WW domain containing transcription regulator 1.
   
 0.971
VGLL4
Vestigial like family member 4.
    
 
 0.917
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
  
  
0.905
TEAD1
TEA domain transcription factor 1.
  
  
0.904
LEF1
Lymphoid enhancer binding factor 1.
    
 0.846
TCF7L1
Transcription factor 7 like 1.
    
 0.831
VGLL1
Vestigial like family member 1.
    
 
 0.756
LATS1
Large tumor suppressor kinase 1.
    
 
 0.730
LATS2
Large tumor suppressor kinase 2.
    
 
 0.662
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.