node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO2 | FMR1 | ENSBTAP00000002068 | ENSBTAP00000058546 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Fragile X mental retardation 1. | 0.837 |
AGO2 | FXR1 | ENSBTAP00000002068 | ENSBTAP00000068817 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Fragile X mental retardation syndrome-related protein 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity). | 0.925 |
AGO2 | FXR2 | ENSBTAP00000002068 | ENSBTAP00000068397 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | FMR1 autosomal homolog 2. | 0.824 |
AGO2 | G3BP1 | ENSBTAP00000002068 | ENSBTAP00000027067 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...] | 0.660 |
CAPRIN1 | FMR1 | ENSBTAP00000022266 | ENSBTAP00000058546 | Caprin-1; May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs; Belongs to the caprin family. | Fragile X mental retardation 1. | 0.735 |
CAPRIN1 | FXR1 | ENSBTAP00000022266 | ENSBTAP00000068817 | Caprin-1; May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs; Belongs to the caprin family. | Fragile X mental retardation syndrome-related protein 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity). | 0.829 |
CAPRIN1 | FXR2 | ENSBTAP00000022266 | ENSBTAP00000068397 | Caprin-1; May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs; Belongs to the caprin family. | FMR1 autosomal homolog 2. | 0.697 |
CAPRIN1 | G3BP1 | ENSBTAP00000022266 | ENSBTAP00000027067 | Caprin-1; May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs; Belongs to the caprin family. | Ras GTPase-activating protein-binding protein 1; ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RN [...] | 0.992 |
CPEB3 | CPEB4 | ENSBTAP00000013178 | ENSBTAP00000013177 | Cytoplasmic polyadenylation element binding protein 3. | Cytoplasmic polyadenylation element binding protein 4. | 0.647 |
CPEB3 | FMR1 | ENSBTAP00000013178 | ENSBTAP00000058546 | Cytoplasmic polyadenylation element binding protein 3. | Fragile X mental retardation 1. | 0.791 |
CPEB3 | FXR1 | ENSBTAP00000013178 | ENSBTAP00000068817 | Cytoplasmic polyadenylation element binding protein 3. | Fragile X mental retardation syndrome-related protein 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity). | 0.811 |
CPEB3 | FXR2 | ENSBTAP00000013178 | ENSBTAP00000068397 | Cytoplasmic polyadenylation element binding protein 3. | FMR1 autosomal homolog 2. | 0.843 |
CPEB4 | CPEB3 | ENSBTAP00000013177 | ENSBTAP00000013178 | Cytoplasmic polyadenylation element binding protein 4. | Cytoplasmic polyadenylation element binding protein 3. | 0.647 |
CPEB4 | FMR1 | ENSBTAP00000013177 | ENSBTAP00000058546 | Cytoplasmic polyadenylation element binding protein 4. | Fragile X mental retardation 1. | 0.824 |
CPEB4 | FXR1 | ENSBTAP00000013177 | ENSBTAP00000068817 | Cytoplasmic polyadenylation element binding protein 4. | Fragile X mental retardation syndrome-related protein 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity). | 0.827 |
CPEB4 | FXR2 | ENSBTAP00000013177 | ENSBTAP00000068397 | Cytoplasmic polyadenylation element binding protein 4. | FMR1 autosomal homolog 2. | 0.824 |
CYFIP1 | CYFIP2 | ENSBTAP00000022470 | ENSBTAP00000011735 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.932 |
CYFIP1 | FMR1 | ENSBTAP00000022470 | ENSBTAP00000058546 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Fragile X mental retardation 1. | 0.990 |
CYFIP1 | FXR1 | ENSBTAP00000022470 | ENSBTAP00000068817 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Fragile X mental retardation syndrome-related protein 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity). | 0.987 |
CYFIP1 | FXR2 | ENSBTAP00000022470 | ENSBTAP00000068397 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | FMR1 autosomal homolog 2. | 0.988 |