Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP3B1 | HPS4 | ENSBTAP00000006605 | ENSBTAP00000050301 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | HPS4, biogenesis of lysosomal organelles complex 3 subunit 2; Hermansky-Pudlak syndrome 4 | 0.674 |
| AP3B1 | LYST | ENSBTAP00000006605 | ENSBTAP00000022355 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | 0.678 |
| AP3B1 | RAB27A | ENSBTAP00000006605 | ENSBTAP00000016464 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | Ras-related protein rab-27a; Bos taurus RAB27A, member RAS oncogene family (RAB27A), mRNA | 0.428 |
| AP3B1 | STX11 | ENSBTAP00000006605 | ENSBTAP00000056178 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | Syntaxin-11; Bos taurus syntaxin 11 (STX11), mRNA; Belongs to the syntaxin family | 0.483 |
| AP3B1 | UNC13D | ENSBTAP00000006605 | ENSBTAP00000018027 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | Protein unc-13 homolog d; Unc-13 homolog D (C. elegans) | 0.473 |
| C7orf25 | GGPS1 | ENSBTAP00000012469 | ENSBTAP00000017376 | UPF0415 protein C7orf25 homolog; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family | Geranylgeranyl diphosphate synthase, type iii; Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family | 0.787 |
| C7orf25 | LYST | ENSBTAP00000012469 | ENSBTAP00000022355 | UPF0415 protein C7orf25 homolog; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | 0.664 |
| GGPS1 | C7orf25 | ENSBTAP00000017376 | ENSBTAP00000012469 | Geranylgeranyl diphosphate synthase, type iii; Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family | UPF0415 protein C7orf25 homolog; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family | 0.787 |
| GGPS1 | LYST | ENSBTAP00000017376 | ENSBTAP00000022355 | Geranylgeranyl diphosphate synthase, type iii; Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | 0.650 |
| HPS4 | AP3B1 | ENSBTAP00000050301 | ENSBTAP00000006605 | HPS4, biogenesis of lysosomal organelles complex 3 subunit 2; Hermansky-Pudlak syndrome 4 | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.674 |
| HPS4 | LYST | ENSBTAP00000050301 | ENSBTAP00000022355 | HPS4, biogenesis of lysosomal organelles complex 3 subunit 2; Hermansky-Pudlak syndrome 4 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | 0.706 |
| HPS4 | TYRP1 | ENSBTAP00000050301 | ENSBTAP00000027945 | HPS4, biogenesis of lysosomal organelles complex 3 subunit 2; Hermansky-Pudlak syndrome 4 | 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin | 0.662 |
| LYST | AP3B1 | ENSBTAP00000022355 | ENSBTAP00000006605 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | AP-3 complex subunit beta-1; Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into [...] | 0.678 |
| LYST | C7orf25 | ENSBTAP00000022355 | ENSBTAP00000012469 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | UPF0415 protein C7orf25 homolog; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family | 0.664 |
| LYST | GGPS1 | ENSBTAP00000022355 | ENSBTAP00000017376 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | Geranylgeranyl diphosphate synthase, type iii; Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family | 0.650 |
| LYST | HPS4 | ENSBTAP00000022355 | ENSBTAP00000050301 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | HPS4, biogenesis of lysosomal organelles complex 3 subunit 2; Hermansky-Pudlak syndrome 4 | 0.706 |
| LYST | RAB27A | ENSBTAP00000022355 | ENSBTAP00000016464 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | Ras-related protein rab-27a; Bos taurus RAB27A, member RAS oncogene family (RAB27A), mRNA | 0.686 |
| LYST | STX11 | ENSBTAP00000022355 | ENSBTAP00000056178 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | Syntaxin-11; Bos taurus syntaxin 11 (STX11), mRNA; Belongs to the syntaxin family | 0.687 |
| LYST | TNFRSF1A | ENSBTAP00000022355 | ENSBTAP00000005522 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | Tumor necrosis factor receptor superfamily member 1a precursor; Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity) | 0.670 |
| LYST | TYRP1 | ENSBTAP00000022355 | ENSBTAP00000027945 | Lysosomal-trafficking regulator; May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules | 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin | 0.614 |
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