node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DARS2 | EPRS1 | ENSBTAP00000005704 | ENSBTAP00000071506 | Aspartate--tRNA ligase, mitochondrial. | Glutamyl-prolyl-tRNA synthetase. | 0.954 |
DARS2 | IARS1 | ENSBTAP00000005704 | ENSBTAP00000001290 | Aspartate--tRNA ligase, mitochondrial. | Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.875 |
DARS2 | IARS2 | ENSBTAP00000005704 | ENSBTAP00000053447 | Aspartate--tRNA ligase, mitochondrial. | Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.913 |
DARS2 | KARS1 | ENSBTAP00000005704 | ENSBTAP00000020818 | Aspartate--tRNA ligase, mitochondrial. | Lysine--tRNA ligase. | 0.756 |
DARS2 | MARS1 | ENSBTAP00000005704 | ENSBTAP00000057583 | Aspartate--tRNA ligase, mitochondrial. | Methionine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.648 |
DARS2 | PARS2 | ENSBTAP00000005704 | ENSBTAP00000050033 | Aspartate--tRNA ligase, mitochondrial. | Prolyl-tRNA synthetase 2, mitochondrial. | 0.904 |
DARS2 | RARS2 | ENSBTAP00000005704 | ENSBTAP00000058548 | Aspartate--tRNA ligase, mitochondrial. | Probable arginine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.926 |
DARS2 | SARS1 | ENSBTAP00000005704 | ENSBTAP00000017232 | Aspartate--tRNA ligase, mitochondrial. | Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16 [...] | 0.511 |
DARS2 | SARS2 | ENSBTAP00000005704 | ENSBTAP00000002334 | Aspartate--tRNA ligase, mitochondrial. | Serine--tRNA ligase, mitochondrial; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. | 0.511 |
DARS2 | YARS1 | ENSBTAP00000005704 | ENSBTAP00000024051 | Aspartate--tRNA ligase, mitochondrial. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.935 |
EPRS1 | DARS2 | ENSBTAP00000071506 | ENSBTAP00000005704 | Glutamyl-prolyl-tRNA synthetase. | Aspartate--tRNA ligase, mitochondrial. | 0.954 |
EPRS1 | IARS1 | ENSBTAP00000071506 | ENSBTAP00000001290 | Glutamyl-prolyl-tRNA synthetase. | Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
EPRS1 | IARS2 | ENSBTAP00000071506 | ENSBTAP00000053447 | Glutamyl-prolyl-tRNA synthetase. | Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
EPRS1 | KARS1 | ENSBTAP00000071506 | ENSBTAP00000020818 | Glutamyl-prolyl-tRNA synthetase. | Lysine--tRNA ligase. | 0.999 |
EPRS1 | MARS1 | ENSBTAP00000071506 | ENSBTAP00000057583 | Glutamyl-prolyl-tRNA synthetase. | Methionine--tRNA ligase, cytoplasmic; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |
EPRS1 | PARS2 | ENSBTAP00000071506 | ENSBTAP00000050033 | Glutamyl-prolyl-tRNA synthetase. | Prolyl-tRNA synthetase 2, mitochondrial. | 0.990 |
EPRS1 | RARS2 | ENSBTAP00000071506 | ENSBTAP00000058548 | Glutamyl-prolyl-tRNA synthetase. | Probable arginine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.996 |
EPRS1 | SARS1 | ENSBTAP00000071506 | ENSBTAP00000017232 | Glutamyl-prolyl-tRNA synthetase. | Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16 [...] | 0.833 |
EPRS1 | SARS2 | ENSBTAP00000071506 | ENSBTAP00000002334 | Glutamyl-prolyl-tRNA synthetase. | Serine--tRNA ligase, mitochondrial; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily. | 0.834 |
EPRS1 | YARS1 | ENSBTAP00000071506 | ENSBTAP00000024051 | Glutamyl-prolyl-tRNA synthetase. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.999 |