STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100GProtein S100-G; Belongs to the S-100 family. (79 aa)    
Predicted Functional Partners:
CALB1
Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
    
 
 0.849
PVALB
Parvalbumin alpha; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity).
    
 
 0.794
CALB2
Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons.
    
 
 0.752
TRPV6
Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.747
TRPV5
Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.731
CALML4
Calmodulin-like protein 4; Belongs to the calmodulin family.
    
 
 0.715
SDF4
45 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
    
 
 0.699
CALM-2
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).
    
 
 0.696
CALML5
Calmodulin like 5.
    
 
 0.695
CALM3
Uncharacterized protein; Belongs to the calmodulin family.
    
 
 0.695
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.