node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AASDH | ACACA | ENSBTAP00000068886 | ENSBTAP00000074493 | Aminoadipate-semialdehyde dehydrogenase. | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | 0.627 |
AASDH | ACSBG2-2 | ENSBTAP00000068886 | ENSBTAP00000012001 | Aminoadipate-semialdehyde dehydrogenase. | AMP-binding domain-containing protein. | 0.654 |
AASDH | ACSL1 | ENSBTAP00000068886 | ENSBTAP00000061904 | Aminoadipate-semialdehyde dehydrogenase. | Acyl-CoA synthetase long chain family member 1. | 0.774 |
AASDH | ACSL3 | ENSBTAP00000068886 | ENSBTAP00000022939 | Aminoadipate-semialdehyde dehydrogenase. | Acyl-CoA synthetase long chain family member 3. | 0.794 |
AASDH | CPT1A | ENSBTAP00000068886 | ENSBTAP00000058061 | Aminoadipate-semialdehyde dehydrogenase. | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. | 0.603 |
AASDH | FASN | ENSBTAP00000068886 | ENSBTAP00000021260 | Aminoadipate-semialdehyde dehydrogenase. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.976 |
AASDH | LPL | ENSBTAP00000068886 | ENSBTAP00000017086 | Aminoadipate-semialdehyde dehydrogenase. | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. Belongs to the AB hydrolase superfamily. Lipase family. | 0.576 |
ACACA | AASDH | ENSBTAP00000074493 | ENSBTAP00000068886 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Aminoadipate-semialdehyde dehydrogenase. | 0.627 |
ACACA | ACSL1 | ENSBTAP00000074493 | ENSBTAP00000061904 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Acyl-CoA synthetase long chain family member 1. | 0.872 |
ACACA | ACSL3 | ENSBTAP00000074493 | ENSBTAP00000022939 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Acyl-CoA synthetase long chain family member 3. | 0.823 |
ACACA | CPT1A | ENSBTAP00000074493 | ENSBTAP00000058061 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. | 0.770 |
ACACA | CPT1B | ENSBTAP00000074493 | ENSBTAP00000021357 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Carnitine O-palmitoyltransferase 1, muscle isoform. | 0.614 |
ACACA | FASN | ENSBTAP00000074493 | ENSBTAP00000021260 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.995 |
ACACA | LPL | ENSBTAP00000074493 | ENSBTAP00000017086 | Acetyl-CoA carboxylase 1; Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP- dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA. | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. Belongs to the AB hydrolase superfamily. Lipase family. | 0.689 |
ACSBG2-2 | AASDH | ENSBTAP00000012001 | ENSBTAP00000068886 | AMP-binding domain-containing protein. | Aminoadipate-semialdehyde dehydrogenase. | 0.654 |
ACSBG2-2 | ACSL1 | ENSBTAP00000012001 | ENSBTAP00000061904 | AMP-binding domain-containing protein. | Acyl-CoA synthetase long chain family member 1. | 0.736 |
ACSBG2-2 | ACSL3 | ENSBTAP00000012001 | ENSBTAP00000022939 | AMP-binding domain-containing protein. | Acyl-CoA synthetase long chain family member 3. | 0.861 |
ACSBG2-2 | CPT1A | ENSBTAP00000012001 | ENSBTAP00000058061 | AMP-binding domain-containing protein. | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. | 0.774 |
ACSBG2-2 | CPT1B | ENSBTAP00000012001 | ENSBTAP00000021357 | AMP-binding domain-containing protein. | Carnitine O-palmitoyltransferase 1, muscle isoform. | 0.729 |
ACSBG2-2 | FASN | ENSBTAP00000012001 | ENSBTAP00000021260 | AMP-binding domain-containing protein. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities as an acyl carrier protein. | 0.927 |