node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEP164 | NEK8 | ENSBTAP00000071722 | ENSBTAP00000020643 | Centrosomal protein 164. | NIMA related kinase 8. | 0.577 |
CEP164 | PLK1 | ENSBTAP00000071722 | ENSBTAP00000019217 | Centrosomal protein 164. | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | 0.886 |
CEP164 | ZNF423 | ENSBTAP00000071722 | ENSBTAP00000023130 | Centrosomal protein 164. | Zinc finger protein 423. | 0.562 |
CTSO | ZNF423 | ENSBTAP00000014691 | ENSBTAP00000023130 | Cathepsin O; Belongs to the peptidase C1 family. | Zinc finger protein 423. | 0.611 |
ELMSAN1 | PLK1 | ENSBTAP00000012216 | ENSBTAP00000019217 | ELM2 and Myb/SANT domain containing 1. | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | 0.598 |
ELMSAN1 | RBL2 | ENSBTAP00000012216 | ENSBTAP00000062088 | ELM2 and Myb/SANT domain containing 1. | RB transcriptional corepressor like 2. | 0.563 |
ELMSAN1 | SND1 | ENSBTAP00000012216 | ENSBTAP00000014154 | ELM2 and Myb/SANT domain containing 1. | Staphylococcal nuclease domain-containing protein 1; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (By similarity). As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (By similarity). Functions as a bridging factor between STAT6 and the basal transcription factor (By similarity). Plays a role in PIM1 regulation of MYB activity (By similarity). Functions as a transcriptional coactivator for STAT5 (By similarity). | 0.614 |
ELMSAN1 | ZNF423 | ENSBTAP00000012216 | ENSBTAP00000023130 | ELM2 and Myb/SANT domain containing 1. | Zinc finger protein 423. | 0.611 |
MTA1 | ZNF219 | ENSBTAP00000069543 | ENSBTAP00000027974 | Metastasis associated 1. | Zinc finger protein 219. | 0.532 |
MTA1 | ZNF423 | ENSBTAP00000069543 | ENSBTAP00000023130 | Metastasis associated 1. | Zinc finger protein 423. | 0.596 |
NEK8 | CEP164 | ENSBTAP00000020643 | ENSBTAP00000071722 | NIMA related kinase 8. | Centrosomal protein 164. | 0.577 |
NEK8 | ZNF423 | ENSBTAP00000020643 | ENSBTAP00000023130 | NIMA related kinase 8. | Zinc finger protein 423. | 0.631 |
PLK1 | CEP164 | ENSBTAP00000019217 | ENSBTAP00000071722 | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | Centrosomal protein 164. | 0.886 |
PLK1 | ELMSAN1 | ENSBTAP00000019217 | ENSBTAP00000012216 | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | ELM2 and Myb/SANT domain containing 1. | 0.598 |
PLK1 | RBL2 | ENSBTAP00000019217 | ENSBTAP00000062088 | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | RB transcriptional corepressor like 2. | 0.578 |
PLK1 | SND1 | ENSBTAP00000019217 | ENSBTAP00000014154 | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | Staphylococcal nuclease domain-containing protein 1; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (By similarity). As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (By similarity). Functions as a bridging factor between STAT6 and the basal transcription factor (By similarity). Plays a role in PIM1 regulation of MYB activity (By similarity). Functions as a transcriptional coactivator for STAT5 (By similarity). | 0.554 |
PLK1 | ZNF423 | ENSBTAP00000019217 | ENSBTAP00000023130 | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | Zinc finger protein 423. | 0.540 |
PPARG | ZNF423 | ENSBTAP00000041555 | ENSBTAP00000023130 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Zinc finger protein 423. | 0.617 |
RBL2 | ELMSAN1 | ENSBTAP00000062088 | ENSBTAP00000012216 | RB transcriptional corepressor like 2. | ELM2 and Myb/SANT domain containing 1. | 0.563 |
RBL2 | PLK1 | ENSBTAP00000062088 | ENSBTAP00000019217 | RB transcriptional corepressor like 2. | Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase- promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, C [...] | 0.578 |