node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP1S1 | CTSZ | ENSBTAP00000074095 | ENSBTAP00000064366 | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity); Belongs to the peptidase C1 family. | 0.539 |
AP1S1 | DNASE2 | ENSBTAP00000074095 | ENSBTAP00000007993 | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family. | 0.616 |
AP1S1 | GNS | ENSBTAP00000074095 | ENSBTAP00000023218 | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.785 |
CTSZ | AP1S1 | ENSBTAP00000064366 | ENSBTAP00000074095 | Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity); Belongs to the peptidase C1 family. | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | 0.539 |
CTSZ | DNASE2 | ENSBTAP00000064366 | ENSBTAP00000007993 | Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity); Belongs to the peptidase C1 family. | Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family. | 0.742 |
CTSZ | GNS | ENSBTAP00000064366 | ENSBTAP00000023218 | Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity); Belongs to the peptidase C1 family. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.736 |
DNASE2 | AP1S1 | ENSBTAP00000007993 | ENSBTAP00000074095 | Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family. | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | 0.616 |
DNASE2 | CTSZ | ENSBTAP00000007993 | ENSBTAP00000064366 | Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family. | Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity); Belongs to the peptidase C1 family. | 0.742 |
DNASE2 | GNS | ENSBTAP00000007993 | ENSBTAP00000023218 | Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.680 |
GLB1 | GNS | ENSBTAP00000020296 | ENSBTAP00000023218 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.938 |
GLB1 | GUSB | ENSBTAP00000020296 | ENSBTAP00000000941 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.502 |
GLB1 | HEXA | ENSBTAP00000020296 | ENSBTAP00000017261 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.978 |
GLB1 | HEXB | ENSBTAP00000020296 | ENSBTAP00000045456 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-hexosaminidase. | 0.970 |
GLB1 | LOC786974 | ENSBTAP00000020296 | ENSBTAP00000045455 | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | Beta-hexosaminidase. | 0.948 |
GNS | AP1S1 | ENSBTAP00000023218 | ENSBTAP00000074095 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity). | 0.785 |
GNS | CTSZ | ENSBTAP00000023218 | ENSBTAP00000064366 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Cathepsin Z; Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Capable of producing kinin potentiating peptides (By similarity); Belongs to the peptidase C1 family. | 0.736 |
GNS | DNASE2 | ENSBTAP00000023218 | ENSBTAP00000007993 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Deoxyribonuclease-2-alpha; Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells (By similarity); Belongs to the DNase II family. | 0.680 |
GNS | GLB1 | ENSBTAP00000023218 | ENSBTAP00000020296 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | 0.938 |
GNS | GUSB | ENSBTAP00000023218 | ENSBTAP00000000941 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. | 0.952 |
GNS | HEXA | ENSBTAP00000023218 | ENSBTAP00000017261 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. | 0.922 |