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KCTD15 protein (Bos taurus) - STRING interaction network
"KCTD15" - BTB/POZ domain-containing protein KCTD15 in Bos taurus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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KCTD15BTB/POZ domain-containing protein KCTD15; During embryonic development, interferes with neural crest formation. Inhibits AP2 transcriptional activity by interaction with its activation domain (By similarity) (283 aa)    
Predicted Functional Partners:
UBE2I
Bos taurus ubiquitin-conjugating enzyme E2I (UBE2I), mRNA; Belongs to the ubiquitin-conjugating enzyme family (158 aa)
       
 
  0.874
SH2B1
Bos taurus SH2B adaptor protein 1 (SH2B1), mRNA (756 aa)
     
   
  0.810
TMEM18
Transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC) (By similarity) (139 aa)
     
   
  0.806
MTCH2
Mitochondrial carrier homolog 2; The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity) (303 aa)
           
  0.799
TFAP2A
Transcription factor AP-2-alpha; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5’-GCCNNNGGC-3’ and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 [...] (437 aa)
     
 
  0.774
GNPDA2
Bos taurus glucosamine-6-phosphate deaminase 2 (GNPDA2), mRNA (276 aa)
           
  0.767
CSMD2
CUB and Sushi multiple domains 2 (3405 aa)
           
  0.730
METTL2B
Methyltransferase-like protein 2; Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs (378 aa)
           
  0.698
FTO
FTO, alpha-ketoglutarate dependent dioxygenase; Bos taurus fat mass and obesity associated (FTO), mRNA (505 aa)
           
  0.693
TFAP2B
Bos taurus transcription factor AP-2 beta (activating enhancer binding protein 2 beta) (TFAP2B), mRNA (460 aa)
     
 
  0.693
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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