STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RIPOR2Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Requ [...] (1050 aa)    
Predicted Functional Partners:
CEP85
Centrosomal protein 85.
      
 0.728
RSL24D1
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
      
 0.656
CMYA5
Cardiomyopathy associated 5.
    
 
 0.645
FAU
Ubiquitin-like protein FUBI.
   
   0.635
ENSBTAP00000061435
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.635
ENSBTAP00000070171
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.635
NPEPL1
Aminopeptidase-like 1.
      
 0.633
GPR157
G protein-coupled receptor 157.
    
 
 0.628
LOC516410
GGNBP1 protein.
      
 0.624
PDZD7
PDZ domain containing 7.
    
 
 0.619
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.