node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CACNG2 | FGF11 | ENSBTAP00000014423 | ENSBTAP00000025624 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. | Acetylcholine receptor subunit beta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.646 |
CHRNA1 | CHRNA2 | ENSBTAP00000024298 | ENSBTAP00000002910 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Cholinergic receptor nicotinic alpha 2 subunit. | 0.778 |
CHRNA1 | CHRNA3 | ENSBTAP00000024298 | ENSBTAP00000004070 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.810 |
CHRNA1 | CHRNA5 | ENSBTAP00000024298 | ENSBTAP00000018151 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.762 |
CHRNA1 | CHRNA7 | ENSBTAP00000024298 | ENSBTAP00000020942 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. | 0.628 |
CHRNA1 | DOK7 | ENSBTAP00000024298 | ENSBTAP00000063739 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Docking protein 7. | 0.731 |
CHRNA1 | FGF11 | ENSBTAP00000024298 | ENSBTAP00000025624 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Acetylcholine receptor subunit beta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.831 |
CHRNA1 | MUSK | ENSBTAP00000024298 | ENSBTAP00000003558 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Muscle associated receptor tyrosine kinase. | 0.707 |
CHRNA1 | RAPSN | ENSBTAP00000024298 | ENSBTAP00000028986 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Receptor associated protein of the synapse. | 0.783 |
CHRNA1 | SLURP1 | ENSBTAP00000024298 | ENSBTAP00000045831 | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Secreted LY6/PLAUR domain containing 1. | 0.900 |
CHRNA2 | CHRNA1 | ENSBTAP00000002910 | ENSBTAP00000024298 | Cholinergic receptor nicotinic alpha 2 subunit. | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.778 |
CHRNA2 | CHRNA3 | ENSBTAP00000002910 | ENSBTAP00000004070 | Cholinergic receptor nicotinic alpha 2 subunit. | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.595 |
CHRNA2 | CHRNA5 | ENSBTAP00000002910 | ENSBTAP00000018151 | Cholinergic receptor nicotinic alpha 2 subunit. | Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.595 |
CHRNA2 | CHRNA7 | ENSBTAP00000002910 | ENSBTAP00000020942 | Cholinergic receptor nicotinic alpha 2 subunit. | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. | 0.715 |
CHRNA2 | FGF11 | ENSBTAP00000002910 | ENSBTAP00000025624 | Cholinergic receptor nicotinic alpha 2 subunit. | Acetylcholine receptor subunit beta; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.630 |
CHRNA2 | SLURP1 | ENSBTAP00000002910 | ENSBTAP00000045831 | Cholinergic receptor nicotinic alpha 2 subunit. | Secreted LY6/PLAUR domain containing 1. | 0.917 |
CHRNA3 | CHRNA1 | ENSBTAP00000004070 | ENSBTAP00000024298 | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.810 |
CHRNA3 | CHRNA2 | ENSBTAP00000004070 | ENSBTAP00000002910 | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Cholinergic receptor nicotinic alpha 2 subunit. | 0.595 |
CHRNA3 | CHRNA5 | ENSBTAP00000004070 | ENSBTAP00000018151 | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Neuronal acetylcholine receptor subunit alpha-5; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | 0.907 |
CHRNA3 | CHRNA7 | ENSBTAP00000004070 | ENSBTAP00000020942 | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. | 0.824 |