• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
GRHPR protein (Bos taurus) - STRING interaction network
"GRHPR" - Bos taurus glyoxylate reductase/hydroxypyruvate reductase in Bos taurus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRHPRBos taurus glyoxylate reductase/hydroxypyruvate reductase (GRHPR), mRNA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family (328 aa)    
Predicted Functional Partners:
HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Catalyzes the final step in the metabolic pathway of hydroxyproline; Belongs to the DapA family (327 aa)
   
 
  0.982
AGXT
Bos taurus alanine-glyoxylate aminotransferase (AGXT), mRNA (414 aa)
 
 
  0.980
GLYCTK
Glycerate kinase; Belongs to the glycerate kinase type-2 family (500 aa)
 
 
  0.961
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (184 aa)
   
  0.938
HAO2
Bos taurus hydroxyacid oxidase 2 (long chain) (HAO2), mRNA; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family (353 aa)
   
 
  0.937
PGP
Glycerol-3-phosphate phosphatase; Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (321 aa)
   
 
  0.935
AGXT2
Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family (514 aa)
   
 
  0.845
DAO
Uncharacterized protein; D-amino-acid oxidase (350 aa)
     
 
  0.826
SDS
L-serine dehydratase/L-threonine deaminase; Serine dehydratase; Belongs to the serine/threonine dehydratase family (327 aa)
     
 
  0.820
SDSL
Bos taurus serine dehydratase-like (SDSL), mRNA (329 aa)
     
 
  0.820
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
Server load: low (13%) [HD]