node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAP2 | ACAP2-2 | ENSBTAP00000004381 | ENSBTAP00000057980 | Uncharacterized protein. | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | 0.918 |
ACAP2 | ARF6 | ENSBTAP00000004381 | ENSBTAP00000056536 | Uncharacterized protein. | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | 0.819 |
ACAP2 | EHD1 | ENSBTAP00000004381 | ENSBTAP00000068009 | Uncharacterized protein. | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary v [...] | 0.505 |
ACAP2 | MICALL1 | ENSBTAP00000004381 | ENSBTAP00000026064 | Uncharacterized protein. | MICAL-like protein 1; Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth (By similarity). | 0.748 |
ACAP2 | RAB35 | ENSBTAP00000004381 | ENSBTAP00000029514 | Uncharacterized protein. | RAB35, member RAS oncogene family. | 0.951 |
ACAP2 | RASA1 | ENSBTAP00000004381 | ENSBTAP00000012583 | Uncharacterized protein. | Ras GTPase-activating protein 1; Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21. | 0.609 |
ACAP2 | RUSC2 | ENSBTAP00000004381 | ENSBTAP00000065221 | Uncharacterized protein. | RUN and SH3 domain containing 2. | 0.717 |
ACAP2-2 | ACAP2 | ENSBTAP00000057980 | ENSBTAP00000004381 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | Uncharacterized protein. | 0.918 |
ACAP2-2 | ARF6 | ENSBTAP00000057980 | ENSBTAP00000056536 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | 0.819 |
ACAP2-2 | EHD1 | ENSBTAP00000057980 | ENSBTAP00000068009 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary v [...] | 0.485 |
ACAP2-2 | MICALL1 | ENSBTAP00000057980 | ENSBTAP00000026064 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | MICAL-like protein 1; Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth (By similarity). | 0.748 |
ACAP2-2 | RAB35 | ENSBTAP00000057980 | ENSBTAP00000029514 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | RAB35, member RAS oncogene family. | 0.945 |
ACAP2-2 | RASA1 | ENSBTAP00000057980 | ENSBTAP00000012583 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | Ras GTPase-activating protein 1; Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21. | 0.536 |
ACAP2-2 | RUSC2 | ENSBTAP00000057980 | ENSBTAP00000065221 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | RUN and SH3 domain containing 2. | 0.716 |
ARF6 | ACAP2 | ENSBTAP00000056536 | ENSBTAP00000004381 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | Uncharacterized protein. | 0.819 |
ARF6 | ACAP2-2 | ENSBTAP00000056536 | ENSBTAP00000057980 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. | 0.819 |
ARF6 | EHD1 | ENSBTAP00000056536 | ENSBTAP00000068009 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | EH domain-containing protein 1; ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary v [...] | 0.784 |
ARF6 | MICALL1 | ENSBTAP00000056536 | ENSBTAP00000026064 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | MICAL-like protein 1; Probable lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, may act as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulation. May be involved in a late step of receptor-mediated endocytosis regulating for instance endocytosed-EGF receptor trafficking. Alternatively, may regulate slow endocytic recycling of endocytosed proteins back to the plasma membrane. May indirectly play a role in neurite outgrowth (By similarity). | 0.595 |
ARF6 | RAB35 | ENSBTAP00000056536 | ENSBTAP00000029514 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | RAB35, member RAS oncogene family. | 0.559 |
ARF6 | RASA1 | ENSBTAP00000056536 | ENSBTAP00000012583 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. | Ras GTPase-activating protein 1; Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21. | 0.719 |