RHBDF1 protein (Bos taurus) - STRING interaction network

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RHBDF1

Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. (856 aa)

Predicted Functional Partners:

RHBDD2

0.783

ADAM17

0.741

RHBDL1

0.741

NPRL3

0.723

SNRNP25

0.715

RHBDD3

0.675

MPG

0.631

TMEM8A

0.619

UBAC2

0.614

FRMD8

0.607

Your Current Organism:

Bos taurus

NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	RHBDF1	ENSBTAP00000001519	ENSBTAP00000063017	ADAM metallopeptidase domain 17.	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	0.741
FRMD8	RHBDF1	ENSBTAP00000033173	ENSBTAP00000063017	FERM domain containing 8.	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	0.607
MPG	NPRL3	ENSBTAP00000037377	ENSBTAP00000022032	N-methylpurine DNA glycosylase.	NPR3 like, GATOR1 complex subunit.	0.607
MPG	RHBDF1	ENSBTAP00000037377	ENSBTAP00000063017	N-methylpurine DNA glycosylase.	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	0.631
MPG	SNRNP25	ENSBTAP00000037377	ENSBTAP00000026387	N-methylpurine DNA glycosylase.	U11/U12 small nuclear ribonucleoprotein 25 kDa protein.	0.606
NPRL3	MPG	ENSBTAP00000022032	ENSBTAP00000037377	NPR3 like, GATOR1 complex subunit.	N-methylpurine DNA glycosylase.	0.607
NPRL3	RHBDF1	ENSBTAP00000022032	ENSBTAP00000063017	NPR3 like, GATOR1 complex subunit.	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	0.723
NPRL3	SNRNP25	ENSBTAP00000022032	ENSBTAP00000026387	NPR3 like, GATOR1 complex subunit.	U11/U12 small nuclear ribonucleoprotein 25 kDa protein.	0.673
NPRL3	TMEM8A	ENSBTAP00000022032	ENSBTAP00000022065	NPR3 like, GATOR1 complex subunit.	Transmembrane protein 8A.	0.732
RHBDD2	RHBDD3	ENSBTAP00000055676	ENSBTAP00000057641	Rhomboid domain containing 2.	Rhomboid domain containing 3.	0.710
RHBDD2	RHBDF1	ENSBTAP00000055676	ENSBTAP00000063017	Rhomboid domain containing 2.	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	0.783
RHBDD2	UBAC2	ENSBTAP00000055676	ENSBTAP00000061446	Rhomboid domain containing 2.	UBA domain containing 2.	0.592
RHBDD3	RHBDD2	ENSBTAP00000057641	ENSBTAP00000055676	Rhomboid domain containing 3.	Rhomboid domain containing 2.	0.710
RHBDD3	RHBDF1	ENSBTAP00000057641	ENSBTAP00000063017	Rhomboid domain containing 3.	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	0.675
RHBDD3	RHBDL1	ENSBTAP00000057641	ENSBTAP00000022975	Rhomboid domain containing 3.	Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.	0.533
RHBDD3	UBAC2	ENSBTAP00000057641	ENSBTAP00000061446	Rhomboid domain containing 3.	UBA domain containing 2.	0.641
RHBDF1	ADAM17	ENSBTAP00000063017	ENSBTAP00000001519	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	ADAM metallopeptidase domain 17.	0.741
RHBDF1	FRMD8	ENSBTAP00000063017	ENSBTAP00000033173	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	FERM domain containing 8.	0.607
RHBDF1	MPG	ENSBTAP00000063017	ENSBTAP00000037377	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	N-methylpurine DNA glycosylase.	0.631
RHBDF1	NPRL3	ENSBTAP00000063017	ENSBTAP00000022032	Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.	NPR3 like, GATOR1 complex subunit.	0.723

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