STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYPD4Ly6/PLAUR domain-containing protein 4. (246 aa)    
Predicted Functional Partners:
DMRTC2
Doublesex- and mab-3-related transcription factor C2; May be involved in sexual development; Belongs to the DMRT family.
   
  
 0.773
CCDC27
Coiled-coil domain containing 27.
      
 0.767
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
      
 0.739
TRIM42
Tripartite motif containing 42.
   
  
 0.721
ZPLD1
Zona pellucida like domain containing 1.
      
 0.697
CBY2
Protein chibby homolog 2; Belongs to the chibby family. SPERT subfamily.
   
  
 0.683
SPACA4
Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Belongs to the SPACA4/bouncer family.
      
 0.683
ZPBP2
Uncharacterized protein.
      
 0.654
SPACA1
Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility.
   
  
 0.634
INSL6
Insulin-like peptide INSL6 A chain; May have a role in sperm development and fertilization. Belongs to the insulin family.
      
 0.633
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.