node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALYREF | NSUN2 | ENSBTAP00000011202 | ENSBTAP00000020559 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.841 |
ALYREF | NSUN3 | ENSBTAP00000011202 | ENSBTAP00000020876 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt- tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5- formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation. | 0.736 |
ALYREF | NSUN4 | ENSBTAP00000011202 | ENSBTAP00000021120 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | 5-methylcytosine rRNA methyltransferase NSUN4; Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4 (B [...] | 0.737 |
ALYREF | NSUN5 | ENSBTAP00000011202 | ENSBTAP00000037133 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | NSUN5 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.752 |
ALYREF | NSUN6 | ENSBTAP00000011202 | ENSBTAP00000029347 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.698 |
ALYREF | NSUN7 | ENSBTAP00000011202 | ENSBTAP00000053492 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.710 |
ALYREF | TRDMT1 | ENSBTAP00000011202 | ENSBTAP00000027378 | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | tRNA (cytosine-5-)-methyltransferase; Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.743 |
DNMT3A | DNMT3L | ENSBTAP00000061971 | ENSBTAP00000019812 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | PHD-type domain-containing protein. | 0.997 |
DNMT3A | NSUN3 | ENSBTAP00000061971 | ENSBTAP00000020876 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt- tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5- formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation. | 0.406 |
DNMT3A | NSUN7 | ENSBTAP00000061971 | ENSBTAP00000053492 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.429 |
DNMT3A | TRDMT1 | ENSBTAP00000061971 | ENSBTAP00000027378 | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | tRNA (cytosine-5-)-methyltransferase; Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.858 |
DNMT3L | DNMT3A | ENSBTAP00000019812 | ENSBTAP00000061971 | PHD-type domain-containing protein. | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.997 |
DNMT3L | TRDMT1 | ENSBTAP00000019812 | ENSBTAP00000027378 | PHD-type domain-containing protein. | tRNA (cytosine-5-)-methyltransferase; Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.872 |
NSUN2 | ALYREF | ENSBTAP00000020559 | ENSBTAP00000011202 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | 0.841 |
NSUN2 | NSUN3 | ENSBTAP00000020559 | ENSBTAP00000020876 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial; Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt- tRNA(Met). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5- formylcytosine (f(5)c) at this position. mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation. | 0.672 |
NSUN2 | NSUN4 | ENSBTAP00000020559 | ENSBTAP00000021120 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 5-methylcytosine rRNA methyltransferase NSUN4; Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4 (B [...] | 0.661 |
NSUN2 | NSUN5 | ENSBTAP00000020559 | ENSBTAP00000037133 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NSUN5 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.764 |
NSUN2 | NSUN6 | ENSBTAP00000020559 | ENSBTAP00000029347 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.858 |
NSUN2 | NSUN7 | ENSBTAP00000020559 | ENSBTAP00000053492 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.865 |
NSUN2 | TRDMT1 | ENSBTAP00000020559 | ENSBTAP00000027378 | NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (cytosine-5-)-methyltransferase; Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.895 |