node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SNAP23 | STX12 | ENSBTAP00000007438 | ENSBTAP00000001580 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | STX12 protein; Belongs to the syntaxin family. | 0.934 |
SNAP23 | STX16-NPEPL1 | ENSBTAP00000007438 | ENSBTAP00000005055 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. | 0.825 |
SNAP23 | STX1A | ENSBTAP00000007438 | ENSBTAP00000003031 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...] | 0.969 |
SNAP23 | STX3 | ENSBTAP00000007438 | ENSBTAP00000065745 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin 3; Belongs to the syntaxin family. | 0.997 |
SNAP23 | STX4 | ENSBTAP00000007438 | ENSBTAP00000009899 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. May also play a role in docking of synaptic vesicles at presynaptic active zones (By similarity). | 0.999 |
SNAP23 | STX5 | ENSBTAP00000007438 | ENSBTAP00000043848 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. | 0.895 |
SNAP23 | STX6 | ENSBTAP00000007438 | ENSBTAP00000027262 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | STX6 protein; Belongs to the syntaxin family. | 0.943 |
SNAP23 | VAMP4 | ENSBTAP00000007438 | ENSBTAP00000073260 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (By similarity). | 0.991 |
SNAP23 | VTI1A | ENSBTAP00000007438 | ENSBTAP00000060590 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Vesicle transport through interaction with t-SNAREs 1A. | 0.843 |
SNAP23 | VTI1B | ENSBTAP00000007438 | ENSBTAP00000056932 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. | 0.889 |
STX12 | SNAP23 | ENSBTAP00000001580 | ENSBTAP00000007438 | STX12 protein; Belongs to the syntaxin family. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.934 |
STX12 | STX16-NPEPL1 | ENSBTAP00000001580 | ENSBTAP00000005055 | STX12 protein; Belongs to the syntaxin family. | t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. | 0.843 |
STX12 | STX1A | ENSBTAP00000001580 | ENSBTAP00000003031 | STX12 protein; Belongs to the syntaxin family. | Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...] | 0.837 |
STX12 | STX3 | ENSBTAP00000001580 | ENSBTAP00000065745 | STX12 protein; Belongs to the syntaxin family. | Syntaxin 3; Belongs to the syntaxin family. | 0.766 |
STX12 | STX4 | ENSBTAP00000001580 | ENSBTAP00000009899 | STX12 protein; Belongs to the syntaxin family. | Syntaxin-4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. May also play a role in docking of synaptic vesicles at presynaptic active zones (By similarity). | 0.900 |
STX12 | STX5 | ENSBTAP00000001580 | ENSBTAP00000043848 | STX12 protein; Belongs to the syntaxin family. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. | 0.892 |
STX12 | STX6 | ENSBTAP00000001580 | ENSBTAP00000027262 | STX12 protein; Belongs to the syntaxin family. | STX6 protein; Belongs to the syntaxin family. | 0.983 |
STX12 | VAMP4 | ENSBTAP00000001580 | ENSBTAP00000073260 | STX12 protein; Belongs to the syntaxin family. | Vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (By similarity). | 0.987 |
STX12 | VTI1A | ENSBTAP00000001580 | ENSBTAP00000060590 | STX12 protein; Belongs to the syntaxin family. | Vesicle transport through interaction with t-SNAREs 1A. | 0.985 |
STX12 | VTI1B | ENSBTAP00000001580 | ENSBTAP00000056932 | STX12 protein; Belongs to the syntaxin family. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. | 0.932 |