STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MFSD10Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump (By similarity); Belongs to the major facilitator superfamily. (460 aa)    
Predicted Functional Partners:
GPAT3
Glycerol-3-phosphate acyltransferase 3.
 
 
  
 0.807
MPG
N-methylpurine DNA glycosylase.
   
  
 0.773
GPAT4
Glycerol-3-phosphate acyltransferase 4; Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (By similarity). Active against both saturated and unsaturated long-chain fatty acyl- CoAs (By similarity); Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
 
 
  
 0.748
ITPRIP
Inositol 1,4,5-trisphosphate receptor-interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release.
      
 0.734
ITPRIPL2
ITPRIP like 2.
      
 0.732
TMX4
Thioredoxin related transmembrane protein 4.
      
 0.723
SMPD4
Sphingomyelin phosphodiesterase 4.
   
  
 0.718
GABRR3
Gamma-aminobutyric acid type A receptor rho3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.693
NT5DC3
5'-nucleotidase domain containing 3.
      
 0.688
SNAPC1
Small nuclear RNA activating complex polypeptide 1.
   
  
 0.671
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.