STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACSF2Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation; Belongs to the ATP-dependent AMP-binding enzyme family. (615 aa)    
Predicted Functional Partners:
MRPL3
39S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.850
MRPL13
39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.
    
 
 0.848
SOD2
Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.843
MRPL24
39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family.
    
   0.842
MRPL47
39S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family.
    
   0.842
MRPL43
39S ribosomal protein L43, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL43 family.
    
   0.842
MRPL21
39S ribosomal protein L21, mitochondrial; Belongs to the bacterial ribosomal protein bL21 family.
    
   0.842
MRPL46
39S ribosomal protein L46, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family.
    
   0.842
MRPL11
39S ribosomal protein L11, mitochondrial; Belongs to the universal ribosomal protein uL11 family.
    
   0.842
DAP3
28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death.
    
   0.823
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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