STRINGSTRING
PRSS2 protein (Bos taurus) - STRING interaction network
"PRSS2" - Anionic trypsin in Bos taurus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PRSS2Anionic trypsin; Bos taurus protease, serine, 2 (trypsin 2) (PRSS2), mRNA; Belongs to the peptidase S1 family (247 aa)    
Predicted Functional Partners:
CTRC
Chymotrypsin-C; Has chymotrypsin-type protease activity and hypocalcemic activity (268 aa)
   
 
0.942
CTSD
Cathepsin D; Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation; Belongs to the peptidase A1 family (412 aa)
         
  0.941
SPTAN1
Spectrin, alpha, non-erythrocytic 1 (2472 aa)
         
  0.928
SERPINA3-1
Serpin A3-1; Potent inhibitor of the serine proteases elastase and trypsin. Moderately inhibits the serine proteases plasmin and chymotrypsin, and the thiol protease proenkephalin-processing enzyme. Does not inhibit the serine proteases cathepsin G, furin, kallikrein, thrombin, tissue plasminogen activator and urokinase, or the cysteine proteases cathepsin B, cathepsin L and papain; Belongs to the serpin family (411 aa)
       
  0.920
MMP9
Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity); Belongs to the peptidase M10A family (712 aa)
       
  0.919
BPI
Bactericidal permeability-increasing protein; The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family (440 aa)
       
  0.916
SERPINA3
Serpin A3-5; Serine protease inhibitor (412 aa)
       
  0.916
ELANE
Bos taurus elastase, neutrophil expressed (ELANE), mRNA; Belongs to the peptidase S1 family (286 aa)
   
 
0.915
HP
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By si [...] (401 aa)
   
   
0.914
ENSBTAG00000047356
Uncharacterized protein; Belongs to the globin family (117 aa)
       
  0.914
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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