STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa)    
Predicted Functional Partners:
SIX1
SIX homeobox 1.
   
 
 0.831
SIX4
SIX homeobox 4.
   
 
 0.815
SIX5
SIX homeobox 5.
   
 
 0.737
SIX2
SIX homeobox 2.
   
 
 0.711
C23H6orf62
Chromosome 6 open reading frame 62 ortholog.
      
 0.664
PPIL6
Probable inactive peptidyl-prolyl cis-trans isomerase-like 6; Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
      
 0.654
MDC1
Mediator of DNA damage checkpoint 1.
     
 0.589
SIX3
SIX homeobox 3.
   
 
 0.580
DACH1
Dachshund family transcription factor 1.
    
 
 0.576
SIX6
SIX homeobox 6.
   
 
 0.570
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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