| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSBTAP00000071774 | SMUG1 | ENSBTAP00000071774 | ENSBTAP00000029297 | Thymidylat_synt domain-containing protein. | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | 0.764 |
| ENSBTAP00000071774 | TK1 | ENSBTAP00000071774 | ENSBTAP00000070231 | Thymidylat_synt domain-containing protein. | Thymidine kinase, cytosolic. | 0.930 |
| ENSBTAP00000071774 | UPRT | ENSBTAP00000071774 | ENSBTAP00000005978 | Thymidylat_synt domain-containing protein. | Uracil phosphoribosyltransferase homolog. | 0.415 |
| MBD4-2 | MPG | ENSBTAP00000028844 | ENSBTAP00000037377 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | N-methylpurine DNA glycosylase. | 0.661 |
| MBD4-2 | NEIL1 | ENSBTAP00000028844 | ENSBTAP00000043635 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | Nei like DNA glycosylase 1. | 0.679 |
| MBD4-2 | SMUG1 | ENSBTAP00000028844 | ENSBTAP00000029297 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | 0.858 |
| MBD4-2 | TDG | ENSBTAP00000028844 | ENSBTAP00000063450 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | Thymine DNA glycosylase. | 0.838 |
| MPG | MBD4-2 | ENSBTAP00000037377 | ENSBTAP00000028844 | N-methylpurine DNA glycosylase. | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | 0.661 |
| MPG | NEIL1 | ENSBTAP00000037377 | ENSBTAP00000043635 | N-methylpurine DNA glycosylase. | Nei like DNA glycosylase 1. | 0.570 |
| MPG | SMUG1 | ENSBTAP00000037377 | ENSBTAP00000029297 | N-methylpurine DNA glycosylase. | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | 0.766 |
| MPG | TDG | ENSBTAP00000037377 | ENSBTAP00000063450 | N-methylpurine DNA glycosylase. | Thymine DNA glycosylase. | 0.636 |
| NEIL1 | MBD4-2 | ENSBTAP00000043635 | ENSBTAP00000028844 | Nei like DNA glycosylase 1. | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | 0.679 |
| NEIL1 | MPG | ENSBTAP00000043635 | ENSBTAP00000037377 | Nei like DNA glycosylase 1. | N-methylpurine DNA glycosylase. | 0.570 |
| NEIL1 | SMUG1 | ENSBTAP00000043635 | ENSBTAP00000029297 | Nei like DNA glycosylase 1. | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | 0.800 |
| NEIL1 | TDG | ENSBTAP00000043635 | ENSBTAP00000063450 | Nei like DNA glycosylase 1. | Thymine DNA glycosylase. | 0.780 |
| NT5E | SMUG1 | ENSBTAP00000071808 | ENSBTAP00000029297 | 5'-nucleotidase; Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | 0.830 |
| NT5E | TYMS | ENSBTAP00000071808 | ENSBTAP00000009214 | 5'-nucleotidase; Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. | Thymidylate synthase; Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. | 0.916 |
| NT5E | UPRT | ENSBTAP00000071808 | ENSBTAP00000005978 | 5'-nucleotidase; Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. | Uracil phosphoribosyltransferase homolog. | 0.927 |
| OAT | SMUG1 | ENSBTAP00000009097 | ENSBTAP00000029297 | Ornithine aminotransferase, mitochondrial. | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | 0.764 |
| SMUG1 | ENSBTAP00000071774 | ENSBTAP00000029297 | ENSBTAP00000071774 | Single-strand selective monofunctional uracil DNA glycosylase; Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5- formy [...] | Thymidylat_synt domain-containing protein. | 0.764 |