node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDX28 | DDX54 | ENSBTAP00000005622 | ENSBTAP00000058322 | DEAD-box helicase 28. | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | 0.681 |
DDX28 | DHX30 | ENSBTAP00000005622 | ENSBTAP00000030598 | DEAD-box helicase 28. | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | 0.841 |
DDX28 | ERAL1 | ENSBTAP00000005622 | ENSBTAP00000020770 | DEAD-box helicase 28. | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | 0.771 |
DDX28 | FASTKD2 | ENSBTAP00000005622 | ENSBTAP00000021553 | DEAD-box helicase 28. | FAST kinase domains 2. | 0.880 |
DDX28 | GRSF1 | ENSBTAP00000005622 | ENSBTAP00000011313 | DEAD-box helicase 28. | G-rich RNA sequence binding factor 1. | 0.830 |
DDX28 | SUPV3L1 | ENSBTAP00000005622 | ENSBTAP00000001386 | DEAD-box helicase 28. | Suv3 like RNA helicase. | 0.488 |
DDX28 | TRMT10C | ENSBTAP00000005622 | ENSBTAP00000033017 | DEAD-box helicase 28. | tRNA methyltransferase 10 homolog C; Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 a [...] | 0.462 |
DDX54 | DDX28 | ENSBTAP00000058322 | ENSBTAP00000005622 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | DEAD-box helicase 28. | 0.681 |
DDX54 | DHX30 | ENSBTAP00000058322 | ENSBTAP00000030598 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | 0.690 |
DHX30 | DDX28 | ENSBTAP00000030598 | ENSBTAP00000005622 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | DEAD-box helicase 28. | 0.841 |
DHX30 | DDX54 | ENSBTAP00000030598 | ENSBTAP00000058322 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | 0.690 |
DHX30 | ERAL1 | ENSBTAP00000030598 | ENSBTAP00000020770 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | 0.699 |
DHX30 | FASTKD2 | ENSBTAP00000030598 | ENSBTAP00000021553 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | FAST kinase domains 2. | 0.806 |
DHX30 | GRSF1 | ENSBTAP00000030598 | ENSBTAP00000011313 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | G-rich RNA sequence binding factor 1. | 0.777 |
DHX30 | PTCD3 | ENSBTAP00000030598 | ENSBTAP00000008498 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | Pentatricopeptide repeat domain-containing protein 3, mitochondrial; Mitochondrial RNA-binding protein that has a role in mitochondrial translation. | 0.717 |
DHX30 | PTPN23 | ENSBTAP00000030598 | ENSBTAP00000003600 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | Protein tyrosine phosphatase non-receptor type 23. | 0.681 |
DHX30 | SSBP1 | ENSBTAP00000030598 | ENSBTAP00000014520 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | Single-stranded DNA-binding protein, mitochondrial; Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA). In vitro, required to maintain the copy number of mitochondrial DNA (mtDNA) and plays crucial roles during mtDNA replication that stimulate activity of the replisome components POLG and TWNK at the replication fork. Promotes the activity of the gamma complex polymerase POLG, largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate POLG activity. In addition it is able to promote the 5 [...] | 0.744 |
DHX30 | SUPV3L1 | ENSBTAP00000030598 | ENSBTAP00000001386 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | Suv3 like RNA helicase. | 0.663 |
DHX30 | TRMT10C | ENSBTAP00000030598 | ENSBTAP00000033017 | ATP-dependent RNA helicase DHX30; RNA dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit. Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Involved in nervous system development and differentiation through its involvement in the up- regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD. Belongs to the DEAD box helicase family. DEAH subfamily. | tRNA methyltransferase 10 homolog C; Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 a [...] | 0.740 |
ERAL1 | DDX28 | ENSBTAP00000020770 | ENSBTAP00000005622 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. | DEAD-box helicase 28. | 0.771 |