node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CASP2 | GABPB1 | ENSBTAP00000068904 | ENSBTAP00000030917 | Caspase 2; Belongs to the peptidase C14A family. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.730 |
CTSB | GABPB1 | ENSBTAP00000036650 | ENSBTAP00000030917 | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.730 |
GABPA | GABPB1 | ENSBTAP00000063258 | ENSBTAP00000030917 | GA binding protein transcription factor, alpha subunit 60kDa. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.997 |
GABPA | YY1 | ENSBTAP00000063258 | ENSBTAP00000027744 | GA binding protein transcription factor, alpha subunit 60kDa. | YY1 transcription factor. | 0.575 |
GABPB1 | CASP2 | ENSBTAP00000030917 | ENSBTAP00000068904 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | Caspase 2; Belongs to the peptidase C14A family. | 0.730 |
GABPB1 | CTSB | ENSBTAP00000030917 | ENSBTAP00000036650 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). | 0.730 |
GABPB1 | GABPA | ENSBTAP00000030917 | ENSBTAP00000063258 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | GA binding protein transcription factor, alpha subunit 60kDa. | 0.997 |
GABPB1 | KIAA0895L | ENSBTAP00000030917 | ENSBTAP00000004579 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | KIAA0895 like. | 0.779 |
GABPB1 | RBM27 | ENSBTAP00000030917 | ENSBTAP00000015463 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | Uncharacterized protein. | 0.608 |
GABPB1 | SMIM7 | ENSBTAP00000030917 | ENSBTAP00000049146 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | Small integral membrane protein 7. | 0.667 |
GABPB1 | TP63 | ENSBTAP00000030917 | ENSBTAP00000020544 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.730 |
GABPB1 | TPD52L2 | ENSBTAP00000030917 | ENSBTAP00000073816 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | TPD52 like 2. | 0.589 |
GABPB1 | TUBB6 | ENSBTAP00000030917 | ENSBTAP00000041770 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | Tubulin beta-6 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.591 |
GABPB1 | YY1 | ENSBTAP00000030917 | ENSBTAP00000027744 | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | YY1 transcription factor. | 0.633 |
KIAA0895L | GABPB1 | ENSBTAP00000004579 | ENSBTAP00000030917 | KIAA0895 like. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.779 |
KIAA0895L | TUBB6 | ENSBTAP00000004579 | ENSBTAP00000041770 | KIAA0895 like. | Tubulin beta-6 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.539 |
RBM27 | GABPB1 | ENSBTAP00000015463 | ENSBTAP00000030917 | Uncharacterized protein. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.608 |
SMIM7 | GABPB1 | ENSBTAP00000049146 | ENSBTAP00000030917 | Small integral membrane protein 7. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.667 |
TP63 | GABPB1 | ENSBTAP00000020544 | ENSBTAP00000030917 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.730 |
TPD52L2 | GABPB1 | ENSBTAP00000073816 | ENSBTAP00000030917 | TPD52 like 2. | GA-binding protein subunit beta-1; Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a a master regulator of nuclear-encoded mitochondrial genes. | 0.589 |