node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGEF38 | PYROXD2 | ENSBTAP00000011590 | ENSBTAP00000072106 | Rho guanine nucleotide exchange factor 38. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.606 |
ARHGEF38 | RNF150 | ENSBTAP00000011590 | ENSBTAP00000069839 | Rho guanine nucleotide exchange factor 38. | Ring finger protein 150. | 0.568 |
BCKDHA | PYROXD2 | ENSBTAP00000021342 | ENSBTAP00000072106 | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.767 |
FDFT1 | PYROXD2 | ENSBTAP00000016504 | ENSBTAP00000072106 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.931 |
GALE | GPD2 | ENSBTAP00000006586 | ENSBTAP00000064800 | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | Glycerol-3-phosphate dehydrogenase, mitochondrial. | 0.428 |
GALE | PYROXD2 | ENSBTAP00000006586 | ENSBTAP00000072106 | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.763 |
GPD2 | GALE | ENSBTAP00000064800 | ENSBTAP00000006586 | Glycerol-3-phosphate dehydrogenase, mitochondrial. | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.428 |
GPD2 | PYROXD2 | ENSBTAP00000064800 | ENSBTAP00000072106 | Glycerol-3-phosphate dehydrogenase, mitochondrial. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.858 |
GPD2 | RALBP1 | ENSBTAP00000064800 | ENSBTAP00000072424 | Glycerol-3-phosphate dehydrogenase, mitochondrial. | RalA binding protein 1. | 0.474 |
NDUFAF6 | PYROXD2 | ENSBTAP00000009959 | ENSBTAP00000072106 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1; Belongs to the NDUFAF6 family. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.922 |
PCMTD1 | PCMTD2 | ENSBTAP00000023247 | ENSBTAP00000042405 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1. | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2. | 0.490 |
PCMTD1 | PYROXD2 | ENSBTAP00000023247 | ENSBTAP00000072106 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.655 |
PCMTD2 | PCMTD1 | ENSBTAP00000042405 | ENSBTAP00000023247 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2. | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1. | 0.490 |
PCMTD2 | PYROXD2 | ENSBTAP00000042405 | ENSBTAP00000072106 | Protein-L-isoaspartate O-methyltransferase domain-containing protein 2. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.626 |
PYROXD2 | ARHGEF38 | ENSBTAP00000072106 | ENSBTAP00000011590 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | Rho guanine nucleotide exchange factor 38. | 0.606 |
PYROXD2 | BCKDHA | ENSBTAP00000072106 | ENSBTAP00000021342 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.767 |
PYROXD2 | FDFT1 | ENSBTAP00000072106 | ENSBTAP00000016504 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | 0.931 |
PYROXD2 | GALE | ENSBTAP00000072106 | ENSBTAP00000006586 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.763 |
PYROXD2 | GPD2 | ENSBTAP00000072106 | ENSBTAP00000064800 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | Glycerol-3-phosphate dehydrogenase, mitochondrial. | 0.858 |
PYROXD2 | NDUFAF6 | ENSBTAP00000072106 | ENSBTAP00000009959 | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1; Belongs to the NDUFAF6 family. | 0.922 |