node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BET1 | SNAP23 | ENSBTAP00000071456 | ENSBTAP00000007438 | Bet1 golgi vesicular membrane trafficking protein. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.764 |
BET1 | SNAP29 | ENSBTAP00000071456 | ENSBTAP00000027666 | Bet1 golgi vesicular membrane trafficking protein. | Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions. | 0.765 |
BET1 | STX17 | ENSBTAP00000071456 | ENSBTAP00000010541 | Bet1 golgi vesicular membrane trafficking protein. | Syntaxin-17; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate [...] | 0.835 |
BET1 | STX4 | ENSBTAP00000071456 | ENSBTAP00000009899 | Bet1 golgi vesicular membrane trafficking protein. | Syntaxin-4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. May also play a role in docking of synaptic vesicles at presynaptic active zones (By similarity). | 0.685 |
BET1 | STX5 | ENSBTAP00000071456 | ENSBTAP00000043848 | Bet1 golgi vesicular membrane trafficking protein. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. | 0.999 |
BET1 | STX7 | ENSBTAP00000071456 | ENSBTAP00000022780 | Bet1 golgi vesicular membrane trafficking protein. | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). | 0.883 |
BET1 | STX8 | ENSBTAP00000071456 | ENSBTAP00000059137 | Bet1 golgi vesicular membrane trafficking protein. | Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER; Belongs to the syntaxin family. | 0.846 |
BET1 | VAMP8 | ENSBTAP00000071456 | ENSBTAP00000032965 | Bet1 golgi vesicular membrane trafficking protein. | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] | 0.990 |
BET1 | VTI1A | ENSBTAP00000071456 | ENSBTAP00000060590 | Bet1 golgi vesicular membrane trafficking protein. | Vesicle transport through interaction with t-SNAREs 1A. | 0.845 |
BET1 | VTI1B | ENSBTAP00000071456 | ENSBTAP00000056932 | Bet1 golgi vesicular membrane trafficking protein. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. | 0.820 |
SNAP23 | BET1 | ENSBTAP00000007438 | ENSBTAP00000071456 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Bet1 golgi vesicular membrane trafficking protein. | 0.764 |
SNAP23 | SNAP29 | ENSBTAP00000007438 | ENSBTAP00000027666 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions. | 0.893 |
SNAP23 | STX17 | ENSBTAP00000007438 | ENSBTAP00000010541 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-17; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate [...] | 0.759 |
SNAP23 | STX4 | ENSBTAP00000007438 | ENSBTAP00000009899 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. May also play a role in docking of synaptic vesicles at presynaptic active zones (By similarity). | 0.999 |
SNAP23 | STX5 | ENSBTAP00000007438 | ENSBTAP00000043848 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter- connected structure of the Golgi apparatus. | 0.895 |
SNAP23 | STX7 | ENSBTAP00000007438 | ENSBTAP00000022780 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). | 0.943 |
SNAP23 | STX8 | ENSBTAP00000007438 | ENSBTAP00000059137 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER; Belongs to the syntaxin family. | 0.891 |
SNAP23 | VAMP8 | ENSBTAP00000007438 | ENSBTAP00000032965 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] | 0.996 |
SNAP23 | VTI1A | ENSBTAP00000007438 | ENSBTAP00000060590 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Vesicle transport through interaction with t-SNAREs 1A. | 0.843 |
SNAP23 | VTI1B | ENSBTAP00000007438 | ENSBTAP00000056932 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. | 0.889 |