STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK1Hook microtubule tethering protein 1. (728 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
   
 0.937
FAM160A2
FTS and Hook-interacting protein; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) (By similarity); Belongs to the UPF0518 family.
    
 0.855
CCDC181
Coiled-coil domain containing 181.
      
 0.837
FAM160B1
Protein FAM160B1; Belongs to the UPF0518 family.
    
 
 0.831
SUN5
Sad1 and UNC84 domain containing 5.
    
 
 0.800
HOOK3
Protein Hook homolog 3.
  
0.785
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 
 0.727
BICDL2
BICD family like cargo adaptor 2.
   
 
 0.727
FAM160A1
Family with sequence similarity 160 member A1.
    
 
 0.715
BICDL1
BICD family like cargo adaptor 1.
    
 
 0.712
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.