STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1249 aa)    
Predicted Functional Partners:
C21H14orf132
Uncharacterized protein.
   
  
 0.691
GNAL
G protein subunit alpha L.
    
 
 0.569
GNAS-2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2 (By similarity). Belongs to the G-alpha family. G(s) subfamily.
    
 
 0.569
LOC112446673
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.568
LOC787600
Keratin, type II cuticular Hb1.
      
 0.568
GPRC5C
G-protein coupled receptor family C group 5 member C; This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G- protein signaling pathways.
      
 0.558
GPC2
Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
   
  
 0.554
TAS2R16
Taste receptor type 2.
      
 0.552
ADAMTSL3
ADAMTS like 3.
   
  
 0.536
GNB4
G protein subunit beta 4.
   
   0.531
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.