node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC42 | GJA1 | ENSBTAP00000059852 | ENSBTAP00000002398 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] | 0.471 |
CDC42 | TUBA1D | ENSBTAP00000059852 | ENSBTAP00000057311 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Detyrosinated tubulin alpha-1D chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | 0.930 |
CFAP45 | EFCAB1 | ENSBTAP00000074384 | ENSBTAP00000073883 | Cilia and flagella associated protein 45. | EF-hand calcium-binding domain-containing protein 1. | 0.861 |
CFAP45 | MBD1 | ENSBTAP00000074384 | ENSBTAP00000004954 | Cilia and flagella associated protein 45. | Methyl-CpG binding domain protein 1. | 0.926 |
CFAP45 | TEKT2 | ENSBTAP00000074384 | ENSBTAP00000028947 | Cilia and flagella associated protein 45. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Belongs to the tektin family. | 0.930 |
CFAP45 | TUBA1D | ENSBTAP00000074384 | ENSBTAP00000057311 | Cilia and flagella associated protein 45. | Detyrosinated tubulin alpha-1D chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | 0.895 |
CFAP45 | TUBB4B | ENSBTAP00000074384 | ENSBTAP00000064454 | Cilia and flagella associated protein 45. | Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.890 |
DCLK1-2 | TUBA1D | ENSBTAP00000050463 | ENSBTAP00000057311 | Uncharacterized protein. | Detyrosinated tubulin alpha-1D chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | 0.972 |
DCLK1-2 | TUBB4B | ENSBTAP00000050463 | ENSBTAP00000064454 | Uncharacterized protein. | Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.971 |
EFCAB1 | CFAP45 | ENSBTAP00000073883 | ENSBTAP00000074384 | EF-hand calcium-binding domain-containing protein 1. | Cilia and flagella associated protein 45. | 0.861 |
EFCAB1 | MBD1 | ENSBTAP00000073883 | ENSBTAP00000004954 | EF-hand calcium-binding domain-containing protein 1. | Methyl-CpG binding domain protein 1. | 0.887 |
EFCAB1 | TEKT2 | ENSBTAP00000073883 | ENSBTAP00000028947 | EF-hand calcium-binding domain-containing protein 1. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Belongs to the tektin family. | 0.869 |
EFCAB1 | TUBA1D | ENSBTAP00000073883 | ENSBTAP00000057311 | EF-hand calcium-binding domain-containing protein 1. | Detyrosinated tubulin alpha-1D chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | 0.904 |
EFCAB1 | TUBB4B | ENSBTAP00000073883 | ENSBTAP00000064454 | EF-hand calcium-binding domain-containing protein 1. | Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.863 |
GJA1 | CDC42 | ENSBTAP00000002398 | ENSBTAP00000059852 | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.471 |
GJA1 | TJP1 | ENSBTAP00000002398 | ENSBTAP00000038633 | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] | Tight junction protein 1; Belongs to the MAGUK family. | 0.976 |
GJA1 | TUBA1D | ENSBTAP00000002398 | ENSBTAP00000057311 | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] | Detyrosinated tubulin alpha-1D chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | 0.901 |
GJA1 | TUBB4B | ENSBTAP00000002398 | ENSBTAP00000064454 | Gap junction alpha-1 protein; Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli a [...] | Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | 0.904 |
MARVELD2 | TJP1 | ENSBTAP00000051825 | ENSBTAP00000038633 | MARVEL domain containing 2. | Tight junction protein 1; Belongs to the MAGUK family. | 0.945 |
MARVELD2 | TUBA1D | ENSBTAP00000051825 | ENSBTAP00000057311 | MARVEL domain containing 2. | Detyrosinated tubulin alpha-1D chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). | 0.900 |