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BID protein (Bos taurus) - STRING interaction network
"BID" - Bos taurus BH3 interacting domain death agonist in Bos taurus
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
BIDBos taurus BH3 interacting domain death agonist (BID), mRNA (193 aa)    
Predicted Functional Partners:
CASP8
Bos taurus caspase 8, apoptosis-related cysteine peptidase (CASP8), mRNA; Belongs to the peptidase C14A family (485 aa)
     
  0.995
BCL2L1
Bos taurus BCL2-like 1 (BCL2L1), mRNA (233 aa)
       
  0.994
BAK1
Bcl-2 homologous antagonist/killer transcript variant 1; Bos taurus BCL2-antagonist/killer 1 (BAK1), mRNA (211 aa)
     
  0.989
BCL2
Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (By similarity). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (By similarity) (229 aa)
       
  0.983
CASP2
Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family (452 aa)
       
  0.979
BAX
Apoptosis regulator BAX; Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production (By similarity). Interacts (via a C-terminal 33 residues) with NOL3 (via CARD domai [...] (192 aa)
     
  0.975
BAD
BCL2-associated agonist of cell death (168 aa)
         
  0.965
BCL2L2
Bcl-2-like protein 2; Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity) (193 aa)
       
 
  0.929
BCL2L11
Bos taurus BCL2-like 11 (apoptosis facilitator) (BCL2L11), mRNA (139 aa)
       
  0.918
GZMB
Uncharacterized protein; Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); Belongs to the peptidase S1 family (266 aa)
       
  0.911
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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