node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIF2AK2 | IFIT1 | ENSBTAP00000011469 | ENSBTAP00000010366 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Interferon induced protein with tetratricopeptide repeats 1. | 0.973 |
EIF2AK2 | IFITM1 | ENSBTAP00000011469 | ENSBTAP00000070867 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Uncharacterized protein. | 0.467 |
EIF2AK2 | IFITM3 | ENSBTAP00000011469 | ENSBTAP00000025311 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Uncharacterized protein. | 0.762 |
EIF2AK2 | IRF9 | ENSBTAP00000011469 | ENSBTAP00000036313 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Interferon-stimulated transcription factor 3, gamma 48kDa. | 0.728 |
EIF2AK2 | ISG15 | ENSBTAP00000011469 | ENSBTAP00000019573 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Ubiquitin-like protein ISG15; Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein. Exhibits antiviral activity towards both DNA and RNA viruses. The secreted form of ISG15 can: induce natural killer cell proliferation, augment lymphokine-activated- killer (LAK) activi [...] | 0.993 |
EIF2AK2 | MX1 | ENSBTAP00000011469 | ENSBTAP00000041289 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Interferon-induced GTP-binding protein Mx1; Interferon-induced dynamin-like GTPase with antiviral activity against rabies virus (RABV), vesicular stomatitis virus (VSV) and murine pneumonia virus (MPV). Isoform 1 but not isoform 2 shows antiviral activity against vesicular stomatitis virus (VSV). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.995 |
EIF2AK2 | MX2 | ENSBTAP00000011469 | ENSBTAP00000011146 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV). | 0.991 |
EIF2AK2 | OAS1Z | ENSBTAP00000011469 | ENSBTAP00000042418 | Eukaryotic translation initiation factor 2-alpha kinase 2. | 25A_SYNTH_3 domain-containing protein. | 0.798 |
EIF2AK2 | RSAD2 | ENSBTAP00000011469 | ENSBTAP00000021373 | Eukaryotic translation initiation factor 2-alpha kinase 2. | Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] | 0.942 |
EIF2AK2 | USP18 | ENSBTAP00000011469 | ENSBTAP00000071973 | Eukaryotic translation initiation factor 2-alpha kinase 2. | USP domain-containing protein; Belongs to the peptidase C19 family. | 0.898 |
IFIT1 | EIF2AK2 | ENSBTAP00000010366 | ENSBTAP00000011469 | Interferon induced protein with tetratricopeptide repeats 1. | Eukaryotic translation initiation factor 2-alpha kinase 2. | 0.973 |
IFIT1 | IFITM1 | ENSBTAP00000010366 | ENSBTAP00000070867 | Interferon induced protein with tetratricopeptide repeats 1. | Uncharacterized protein. | 0.742 |
IFIT1 | IFITM3 | ENSBTAP00000010366 | ENSBTAP00000025311 | Interferon induced protein with tetratricopeptide repeats 1. | Uncharacterized protein. | 0.804 |
IFIT1 | IRF9 | ENSBTAP00000010366 | ENSBTAP00000036313 | Interferon induced protein with tetratricopeptide repeats 1. | Interferon-stimulated transcription factor 3, gamma 48kDa. | 0.784 |
IFIT1 | ISG15 | ENSBTAP00000010366 | ENSBTAP00000019573 | Interferon induced protein with tetratricopeptide repeats 1. | Ubiquitin-like protein ISG15; Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein. Exhibits antiviral activity towards both DNA and RNA viruses. The secreted form of ISG15 can: induce natural killer cell proliferation, augment lymphokine-activated- killer (LAK) activi [...] | 0.982 |
IFIT1 | MX1 | ENSBTAP00000010366 | ENSBTAP00000041289 | Interferon induced protein with tetratricopeptide repeats 1. | Interferon-induced GTP-binding protein Mx1; Interferon-induced dynamin-like GTPase with antiviral activity against rabies virus (RABV), vesicular stomatitis virus (VSV) and murine pneumonia virus (MPV). Isoform 1 but not isoform 2 shows antiviral activity against vesicular stomatitis virus (VSV). Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.969 |
IFIT1 | MX2 | ENSBTAP00000010366 | ENSBTAP00000011146 | Interferon induced protein with tetratricopeptide repeats 1. | Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV). | 0.945 |
IFIT1 | OAS1Z | ENSBTAP00000010366 | ENSBTAP00000042418 | Interferon induced protein with tetratricopeptide repeats 1. | 25A_SYNTH_3 domain-containing protein. | 0.862 |
IFIT1 | RSAD2 | ENSBTAP00000010366 | ENSBTAP00000021373 | Interferon induced protein with tetratricopeptide repeats 1. | Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] | 0.929 |
IFIT1 | USP18 | ENSBTAP00000010366 | ENSBTAP00000071973 | Interferon induced protein with tetratricopeptide repeats 1. | USP domain-containing protein; Belongs to the peptidase C19 family. | 0.914 |