STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEP120Centrosomal protein of 120 kDa; Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity). Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK [...] (987 aa)    
Predicted Functional Partners:
SPICE1
Spindle and centriole-associated protein 1; Regulator required for centriole duplication. for proper bipolar spindle formation and chromosome congression in mitosis (By similarity).
   
 
 0.923
CEP162
Centrosomal protein 162.
   
 
 0.838
SAXO1
Stabilizer of axonemal microtubules 1.
    
 
 0.806
POC5
POC5 centriolar protein.
   
  
 0.806
POC1B
POC1 centriolar protein B.
    
 
 0.803
CEP63
Centrosomal protein 63.
   
  
 0.799
CEP135
Centrosomal protein 135.
   
 
 0.794
CEP164
Centrosomal protein 164.
    
 
 0.793
RTTN
Rotatin.
   
  
 0.780
CEP350
Centrosomal protein 350.
   
 
 0.777
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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