STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CATHL4Cathelicidin 4. (144 aa)    
Predicted Functional Partners:
CATHL1
Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms; Belongs to the cathelicidin family.
  
  
0.920
CATHL2
Cathelicidin-2; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.
  
  
0.885
LOC112443481
Cathelicidin-4; Potent microbicidal activity; active against S.aureus and E.coli; Belongs to the cathelicidin family.
  
 
  
0.801
BPIFA2A
Short palate, lung and nasal epithelium carcinoma-associated protein 2A; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
   
  
 0.757
KRTAP9-1
Uncharacterized protein.
      
 0.687
KRTAP9-2
Keratin associated protein 9-2.
      
 0.684
CATHL6
Cathelicidin-6; Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi; Belongs to the cathelicidin family.
  
  
0.682
LAP
Lingual antimicrobial peptide; Shows a broad spectrum of antibacterial and antifungal activities; Belongs to the beta-defensin family. LAP/TAP subfamily.
   
  
 0.668
APOL3
APOL3 protein.
      
 0.665
PGLYRP1
Peptidoglycan recognition protein 1; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
   
  
 0.665
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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