node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD16B | ARFRP1 | ENSBTAP00000055253 | ENSBTAP00000009858 | Chromosome 20 open reading frame 135 ortholog. | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | 0.621 |
ABHD16B | DNAJC5 | ENSBTAP00000055253 | ENSBTAP00000059567 | Chromosome 20 open reading frame 135 ortholog. | DnaJ homolog subfamily C member 5; Acts as a general chaperone in regulated exocytosis. Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity). Involved in the calcium-mediated control of a late stage of exocytosis (By similarity). May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). | 0.510 |
ABHD16B | FNDC11 | ENSBTAP00000055253 | ENSBTAP00000069147 | Chromosome 20 open reading frame 135 ortholog. | Fibronectin type III domain-containing protein 11. | 0.785 |
ABHD16B | GMEB2 | ENSBTAP00000055253 | ENSBTAP00000019648 | Chromosome 20 open reading frame 135 ortholog. | Glucocorticoid modulatory element binding protein 2. | 0.655 |
ABHD16B | KCNQ2 | ENSBTAP00000055253 | ENSBTAP00000067696 | Chromosome 20 open reading frame 135 ortholog. | Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. | 0.480 |
ABHD16B | LIME1 | ENSBTAP00000055253 | ENSBTAP00000009867 | Chromosome 20 open reading frame 135 ortholog. | Uncharacterized protein. | 0.690 |
ABHD16B | PTK6 | ENSBTAP00000055253 | ENSBTAP00000053595 | Chromosome 20 open reading frame 135 ortholog. | Tyrosine-protein kinase. | 0.505 |
ABHD16B | RTEL1 | ENSBTAP00000055253 | ENSBTAP00000028108 | Chromosome 20 open reading frame 135 ortholog. | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] | 0.463 |
ABHD16B | SLC2A4RG | ENSBTAP00000055253 | ENSBTAP00000072273 | Chromosome 20 open reading frame 135 ortholog. | SLC2A4 regulator. | 0.651 |
ABHD16B | ZGPAT | ENSBTAP00000055253 | ENSBTAP00000009860 | Chromosome 20 open reading frame 135 ortholog. | Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity). | 0.660 |
ARFRP1 | ABHD16B | ENSBTAP00000009858 | ENSBTAP00000055253 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Chromosome 20 open reading frame 135 ortholog. | 0.621 |
ARFRP1 | FNDC11 | ENSBTAP00000009858 | ENSBTAP00000069147 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Fibronectin type III domain-containing protein 11. | 0.685 |
ARFRP1 | GMEB2 | ENSBTAP00000009858 | ENSBTAP00000019648 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Glucocorticoid modulatory element binding protein 2. | 0.814 |
ARFRP1 | LIME1 | ENSBTAP00000009858 | ENSBTAP00000009867 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Uncharacterized protein. | 0.569 |
ARFRP1 | PTK6 | ENSBTAP00000009858 | ENSBTAP00000053595 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Tyrosine-protein kinase. | 0.591 |
ARFRP1 | RTEL1 | ENSBTAP00000009858 | ENSBTAP00000028108 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] | 0.505 |
ARFRP1 | SLC2A4RG | ENSBTAP00000009858 | ENSBTAP00000072273 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | SLC2A4 regulator. | 0.502 |
ARFRP1 | ZGPAT | ENSBTAP00000009858 | ENSBTAP00000009860 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. | Zinc finger CCCH-type with G patch domain-containing protein; Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity). | 0.801 |
DNAJC5 | ABHD16B | ENSBTAP00000059567 | ENSBTAP00000055253 | DnaJ homolog subfamily C member 5; Acts as a general chaperone in regulated exocytosis. Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity). Involved in the calcium-mediated control of a late stage of exocytosis (By similarity). May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). | Chromosome 20 open reading frame 135 ortholog. | 0.510 |
DNAJC5 | FNDC11 | ENSBTAP00000059567 | ENSBTAP00000069147 | DnaJ homolog subfamily C member 5; Acts as a general chaperone in regulated exocytosis. Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity). Involved in the calcium-mediated control of a late stage of exocytosis (By similarity). May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity). | Fibronectin type III domain-containing protein 11. | 0.569 |