STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCAPERS-phase cyclin A associated protein in the ER. (756 aa)    
Predicted Functional Partners:
RCN2
Reticulocalbin 2, EF-hand calcium binding domain.
      
 0.792
GSG1
Germ cell-specific gene 1 protein; May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum; Belongs to the GSG1 family.
      
 0.744
PLEKHM3
Pleckstrin homology domain containing M3.
   
  
 0.680
XRRA1
X-ray radiation resistance-associated protein 1; May be involved in the response of cells to X-ray radiation.
      
 0.664
FAM124B
Protein FAM124B; Belongs to the FAM124 family.
      
 0.659
SAAL1
Serum amyloid A like 1.
      
 0.652
CCNA2
Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
    
 
 0.646
PEAK1
Pseudopodium enriched atypical kinase 1.
      
 0.646
TSPAN3
Tetraspanin-3; Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
      
 0.637
CABLES2
Cdk5 and Abl enzyme substrate 2.
      
 0.620
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.