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RANBP10 protein (Bos taurus) - STRING interaction network
"RANBP10" - Ran-binding protein 10 in Bos taurus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
RANBP10Ran-binding protein 10; Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function. May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1 (By similarity); Belongs to the RANBP9/10 family (620 aa)    
Predicted Functional Partners:
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1384 aa)
     
  0.922
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1; Son of sevenless homolog 1 (Drosophila) (1333 aa)
     
    0.910
HGF
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity) (730 aa)
         
  0.905
HRAS
HRas proto-oncogene, GTPase; Harvey rat sarcoma viral oncogene homolog (246 aa)
     
 
  0.905
NRAS
NRAS proto-oncogene, GTPase; Bos taurus neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS), mRNA (189 aa)
     
 
  0.904
RANBP9
RAN binding protein 9 (538 aa)
       
0.903
KRAS
KRAS proto-oncogene, GTPase; Kirsten rat sarcoma viral oncogene homolog (188 aa)
     
 
  0.902
RMND5A
Required for meiotic nuclear division 5 homolog A (S. cerevisiae) (391 aa)
     
 
  0.865
WDR26
Bos taurus WD repeat domain 26 (WDR26), mRNA (514 aa)
     
 
  0.863
NACC1
Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (532 aa)
     
   
  0.856
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
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