node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCSER2 | DYDC1 | ENSBTAP00000023416 | ENSBTAP00000043925 | Coiled-coil serine rich protein 2. | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | 0.784 |
CCSER2 | DYDC2 | ENSBTAP00000023416 | ENSBTAP00000043930 | Coiled-coil serine rich protein 2. | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | 0.738 |
CCSER2 | GHITM | ENSBTAP00000023416 | ENSBTAP00000043881 | Coiled-coil serine rich protein 2. | Growth hormone inducible transmembrane protein; Belongs to the BI1 family. | 0.676 |
DPY30 | DYDC1 | ENSBTAP00000012183 | ENSBTAP00000043925 | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | 0.641 |
DPY30 | DYDC2 | ENSBTAP00000012183 | ENSBTAP00000043930 | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | 0.743 |
DPY30 | PAGR1 | ENSBTAP00000012183 | ENSBTAP00000042638 | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned. During immunoglobulin class switching in activated B [...] | 0.737 |
DPY30 | WDR5 | ENSBTAP00000012183 | ENSBTAP00000061141 | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). | WD repeat-containing protein 5; Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity). In association with RBBP5 and ASH2L, stimulates the histone methyltr [...] | 0.999 |
DYDC1 | CCSER2 | ENSBTAP00000043925 | ENSBTAP00000023416 | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | Coiled-coil serine rich protein 2. | 0.784 |
DYDC1 | DPY30 | ENSBTAP00000043925 | ENSBTAP00000012183 | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). | 0.641 |
DYDC1 | DYDC2 | ENSBTAP00000043925 | ENSBTAP00000043930 | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | 0.697 |
DYDC1 | GHITM | ENSBTAP00000043925 | ENSBTAP00000043881 | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | Growth hormone inducible transmembrane protein; Belongs to the BI1 family. | 0.726 |
DYDC1 | NME5 | ENSBTAP00000043925 | ENSBTAP00000011530 | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | NME/NM23 family member 5; Belongs to the NDK family. | 0.558 |
DYDC1 | WDR5 | ENSBTAP00000043925 | ENSBTAP00000061141 | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | WD repeat-containing protein 5; Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity). In association with RBBP5 and ASH2L, stimulates the histone methyltr [...] | 0.571 |
DYDC2 | CCSER2 | ENSBTAP00000043930 | ENSBTAP00000023416 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | Coiled-coil serine rich protein 2. | 0.738 |
DYDC2 | DPY30 | ENSBTAP00000043930 | ENSBTAP00000012183 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In embryonic stem cells, may play a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport (By similarity). | 0.743 |
DYDC2 | DYDC1 | ENSBTAP00000043930 | ENSBTAP00000043925 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis. Belongs to the dpy-30 family. | 0.697 |
DYDC2 | GHITM | ENSBTAP00000043930 | ENSBTAP00000043881 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | Growth hormone inducible transmembrane protein; Belongs to the BI1 family. | 0.695 |
DYDC2 | JADE2 | ENSBTAP00000043930 | ENSBTAP00000063034 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | Jade family PHD finger 2. | 0.633 |
DYDC2 | LRWD1 | ENSBTAP00000043930 | ENSBTAP00000019617 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | Leucine rich repeats and WD repeat domain containing 1. | 0.631 |
DYDC2 | NME5 | ENSBTAP00000043930 | ENSBTAP00000011530 | DPY30 domain-containing protein 2; Belongs to the dpy-30 family. | NME/NM23 family member 5; Belongs to the NDK family. | 0.800 |