STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSTR5Somatostatin receptor type 5; Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization (By similarity) (368 aa)    
Predicted Functional Partners:
SST
Somatostatin; Somatostatin inhibits the release of somatotropin
   
 0.990
CORT
Bos taurus cortistatin (CORT), mRNA
    
 0.958
RLN3
Relaxin 3
    
 0.949
GRM7
Uncharacterized protein; Bos taurus glutamate receptor, metabotropic 7 (GRM7), mRNA
    
 0.943
POMC
Pro-opiomelanocortin; Corticotropin: Stimulates the adrenal glands to release cortisol
   
 0.941
HRH3
Histamine receptor H3; Belongs to the G-protein coupled receptor 1 family
   
 
 0.936
GRM6
Glutamate receptor, metabotropic 6
    
 0.932
DRD2
D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family
   
0.929
NPY
Pro-neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone
   
 0.928
TAS2R4
Bos taurus taste receptor, type 2, member 4 (TAS2R4), mRNA
     
 0.928
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, domestic cattle, domestic cow
Server load: low (7%) [HD]